NURSERY DZ Flashcards
piglets are separated from sow at what age?
24-28 d/o (6 kg) → 78-84 d/0 (18-20 kg)
epidemic triangle
Agent
Host
Environment
T/F: vax pigs have a low likelihood of diarrhea
T
nursery pigs age
weaning up to 80d
why piglets are the most susceptible to dz?
- unable to thermoregulate
- developing bodily fx (immune system, GIT)
- rely on maternal Abs
disadvantages of solid wet concrete
- poor insulator
- more exposed to stress factors
advantages of wooden slat (impractical in PH)
- higher resistance
_____________ concrete is used in the PH
metal
cold stress dz can lead to?
diarrhea and respi dz
feeds are not properly digested if these enzymes are low
amylase and lipase
T/F: vax against dz not present in your area is practical
T - should be skipped
swine blood collection site
- aorta (risky)
- jugular v. (favored)
- ear v. (collapses easily)
how long do piglets stay in the farrowing pen?
5-7d
ideal time for transferring piglets to nursery
cooler time of the day (early morning or late afternoon)
condition where piglets after weaning refuse to eat and can be depressed resulting to decreased feed and water intake, and weight gain
weaning lag
water intake after weaning:
Day 1 = ?
Day 2-3 = ?
- drop
- increase
if diarrhea is observed, dry feed should be withdrawn and wet feeding should be done during _____________
morning
gruel combination
1 kg feed + 8 L water + 50 g electrolytes
PRRS effects on early mid-term and late-term sows
early = little adverse
late = SMEDI
T/F: piglets that have PRRS and survived in utero infxn die early due to respi distress
T
Infected piglets with PRRS in womb are not expected to live long due to _________
interstitial pneumonia
MOT of PRRS
direct contact, feces, oral and nasal secretions, semen, fomites, aerosol
3 stages of PRRS
- acute - viremia target cells attacked (LO, MO)
- persistence - subclinical, decreased shedding and viremia stops
- extinction - end of shedding, cleared, body manages to fight the virus
persistent infxn whrein the virus is eventually cleared (_________ DPI)
chronic persistent infxn (100-145 DPI)
where does PRRS virus replicate?
MO and lymphoid tissue
mechanisms to subvert immune response
- inhibit caspase-dependent apoptosis
- suppress type-1 interferon response - for cell death
- use of decoy epitopes (limits neutralizing Ab response)
PRRS characteristic lesion
interstitial pneumonia + LN enlargement
PRRS diagnosis
CS, ELISA, immunohistochem, RT-PCR, VN (virus neutralization) assay
how long is herd (infected w/ PRRS) closure
26 weeks
T/F: total depopulation should be done to farms infected w/ PRRS
F - partial (test and remove)
T/F: pigs who recovered from PRRS are typically immune
T
PRRS virus are susceptible to?
phenols, glutaraldehyde, phenolics, quaternary
T/F: PRRS virus is easily destroyed in dry fomites
T
other term for PRRS
mystery pig dz, blue ear pig dz
causative agent of mycoplasma pneumonia
Mycoplasma hyopneumoniae
other term for mycoplasma pneumonia
porcine enzootic pneumonia
- lethal pneumonia affecting piglets
- coughing, dyspnea, wasting
mycoplasma pneumonia lesions are concentrated on the _________ portions of the lungs (w/out necrotic areas)
apical
T/F: mycoplasma pneumonia can be transmitted horizontally and vertically
T
T/F: mycoplasma pneumonia is prone to secondary infxn
T - Haemophilus, Pasteurella
Mycoplasma pneumonia diagnosis
CS, isolation, serology, PCR
waste materials can accumulate _______
ammonia - can destroy galvanized iron
causative agent of porcine pleuropneumonia
Actinobacillus pleuropneumoniae or Haemophilus pleuropneumoniae
other term for porcine pleuropneumoniae
APP (actinobacillus pleuropneumoniae) - causing fatal fibrinous, hemorrhagic, necrotizing pneumonia, lung hemorrhaging, fibrinous exudation
APP is eradicated in ______
North America
APP CS
bloody exudates
MOT of APP
direct contact, droplets, subclinical carriers
APP virulence factors
- RTX and APX toxin
- capsular factors
- fimbriae
- adhesins
- LPS
- hemolysin
- cytotoxin
- permeability factors
O antigen inhibits _____
phagocytosis
virulence factors can cause
- pores in CM
- damage capillaries and alveolar walls
- vascular leakage
- thrombosis
- impaired phagocytic fxn
- failure of clearance mechanisms
T/F: Mycoplasma infxn can cause necrotic lesions
F
APP diagnosis
CS, necropsy, serology, isolation