NURS 405 Week 6 Monday Flashcards
Dysfunction of the endocrine gland itself
Hyposecretion / Hypersecretion
Dysfunction in feedback system
Fail to give proper feedback
May respond to inappropriate signals
Dysfunction in transport of the hormone in blood
Hormone may be degraded at an alterted rate (too fast)
Hormone may be attacked (inactivated) by antibodies before it signals the target cell
Dysfunction in the delivery of the hormone to the target tissue
Inadequate blood supply to the target tissue
FBG levels
> 126 mg /dL –> diabetes
Fasting blood glucose after fasting for more than 8 hours
Avoid tea / coffee because caffeine mobilizes resources and puts nutrients in the blood
Caffeine lowers insulin sensitivity –> increase BG
2 Hour BG < *** mg/dL following 75g OGTT
140 is the max for a person without diabetes
>200 –> diabetes
A1C ideal level is?
What is A1C for diabetes dx?
5.7%
6.0 –> 126
6.5 –> 140 (>6.5 –> Diabetes)
7.0 –> 154
7.5 –> 169
10 –> 240
Random BG for DM diagnosis
> 200 mg/dL
Prediabetes Diagnostic Levels
FBG?
2 hour BG 75g OTTT
A1C
Any test value between normal values and values diagnostic of diabetes is considered to be indicative of prediabetes
FBG 100-125 mg/ dL
2 Hours 140-199 mg / dL
A1c- 5.7-6.4%
Criteria for screening for diabetes or prediabetes in asymptomatic adults
- Overweight / Obese patients (BMI > 25 ) or BMI > 23 (Asians)
Risk factors - A1c > 5.7%
- 1st degree relative with DM
- High risk race: African American, Latino, Native American, Asian American, Pacific Islander
- Women w/ hx GDM or PCOS (polycystic ovarian syndrome)
- Hx CVD, HTN, dyslipidemia (HDL <35 mg/dL & trig >250 mg/dL)
- Physical inactivity
- Insulin resistance - acanthosis nigricans
Signs of Hyperglycemia 3 Ps
Polyuria - increased urination
Polydipsia - increased thirst
Polyphagia - increased hunger
Classic symptoms of hypoglycemia
Shakiness Dizziness Lightheadedness Hunger Confusion Irritability
When should insulin therapy be initiated?
Persistent hyperglycemia > 180 BG. Target glucose range 140-180
More stringent goals 110-140 BG appropriate for selected patients if they can avoid hypoglycemia
How often do you check BG when someone is on IV insulin?
Q 30mins - 2hrs
What is the preferred treatment for noncritically ill hospitalized patients with poor oral intake or those who are taking nothing by mouth?
Basal insulin or basal plus bolus correction insulin regimen is the preferred treatment