Numbers Flashcards
what is the onset of midadolam?
30-60 seconds
what is the duration of midazolam?
15-80 minutes
What is the onset of lorazepam?
1-2 minutes
What is the duration of lorazepam?
6-10 hours
What percent of receptors bound by midazolam gives anxiolysis?
20-30%
What percent of receptors bound by midazolam causes sedation?
30-50%
What percent of receptors bound by midazolam causes unconsciousness?
60%
What is the PO dose of midazolam for kids?
0.5mg/kg up to 15mg
What dose of Midazolam is used for IV sedation?
0.5-4mg initial dose then 1-7mg/hour
What dose of midazolam is used for IV induction?
0.1-0.2mg/kg
What dose of Diazepam is used for suppression of siezure activity?
0.1mg/kg
What % of oral Midaz makes it past 1st pass?
50%
how much of midaz is bound to protein?
90-98%
what is the pK of midaz?
6.15
What is the dose of flumazenil?
0.1-0.2 mg repeated up to 3 mg
what is the pH of thiopental?
10.5
What is the onset of thiopental?
30-40 seconds
what is the duration of thiopental?
5-8 minutes
What % of thiopental is bound to protein?
80%
what is the IV induction dose of methohexital?
1-1.5mg/kg
What is a rectal dose of methohexital?
20-30mg/kg
What are the components of Proopofol?
1% propofol 10% soybean oil 2.25% glycerol 1.2% egg lecithin 0.005% disodium edetate
What is the induction dose of propofol?
1-2.5mg/kg
What is the onset of propofol?
30 seconds
Waht is the duration of propofol?
4-8 minutes
What is the distribution half life of propofol?
2-8 minutes
What % of propofol is metabolized by the liver?
70%
What % of propofol is metabolized in the lungs?
30%
What % of propofol is protein bound?
98%
What is an IV sedation dose of propofol?
25-100mcg/kg/min
What is a TIVA dose of propofol?
100-200mcg/kg/min
What % of etomidate is glycerol?
35%
What is the onset of etomidate?
30 seconds
What is the duration of etomidate?
4-8 minutes
What % of etomidate is bound to protein?
76%
What is the elimination half time of etomidate?
2.6 hours
What is the IV onset of ketamine?
30 seconds
What is the IM onset of ketamine?
3-4 minutes
What is the Duration of ketamine IV?
5-10 (or 10-15 depending on the slide)
What is the IM duration of ketamine?
12-25 min
What is the elimination time of ketamine?
2.5 hours
What % of ketamine is protein bound?
27%
What is an analgesia subanesthetic dose of ketamine?
0.1-0.5 mg/kg/hour
What is the IV induction dose of ketamine?
1-2mg/kg
What is the IM induction dose of ketamine?
4-8mg/kg
