Number one Flashcards
Gene associated with Alcohol Dependence
GABRA2
Genes involved in alcohol metabolism and if mutated, increase the patient risk of getting an upper GI cancer
ALDH1B & ALDH2
Gene linked to Amgdala activation and linked to psychiatric issues in alcohol abuse
SLC6A4
Greater reduction of heavy drinking in alcohol abuse prescribed Noltrexone
OPRM1
Role of therapist in 12 step Facilitation program
To educate and encourage the patient to attend
Amitriptyline interaction
Marijuana and anticholinergic
Action of Benzodiazepine- direct or indirect
Indirect GABA Receptor agonist
Does Naltrexone require dose adjustment in mild to moderate hepatic impairment
No
For Alcohol detox are patients more likely to complete detox as inpatient or outpatient
Inpatient
Which race Has highest level of cannabis abuse
Native Americans
Opioid peptides include
Dynorphins, Endorphins, and Enkephalins
Gene involved in high susceptibility to cocaine addiction
CAMK4
Heroin overdose can we mimic
End stage liver disease
Which medication helps in reducing marijuana withdrawal symptoms and marijuana use
Gallivanting
Percentage of cases of marijuana with genetic linkage
58% to 67%
How many percent of alcoholic hepatitis progress to cirrhosis
80%
Chronic use of cocaine leads to cocaine-induced dystonic reactions
Reduces number of D1 receptors in the striatal pathway
Treatment is Benzodiazepines
MATRIX Intensive Outpatient program
- employs multiple treatment approaches including the 12-step model, family therapy, CBT, and psychoeducation.
- 16-week matrix intensive outpatient treatment program
- has 8 early recovery skills group sessions to help clients develop more efficient ways of changing their behavior and staying abstinent.
- 12 family education group sessions and 3 individual family sessions.
Modified Minnesota Detoxification Scale (mMINDS).
The mMINDS is used to assess the severity of alcohol withdrawal syndrome in patients admitted to the ICU or who are unable to answer verbally.
Wernicke encephalopathy triad includes
- Opthalmoplegia
- Ataxia
- Confusion
ANI- Alcoholic and non Alchoholic Liver disease index is based on
mean corpuscular volume, aspartate transaminase (AST) and alanine transaminase (ALT) ratio, body mass index, and gender
HIV prevention
Tenofivir plus emtricitabine
West Haven criteria
- grading of mental state in patients with cirrhosis.
grade 2 hepatic encephalopathy present with lethargy, disorientation to time, personality changes, and inappropriate behavior.
Grade 0 is incorrect because at grade 0 the patient will present with normal mental status without any abnormalities or changes in personality or behavior.
Grade 1 is incorrect because the patient with grade 1 hepatic encephalopathy lacks awareness, is euphoric or anxious, have a short attention span, and impaired addition or subtraction without obvious personality changes.
Grade 3 is incorrect because patients with grade 3 hepatic encephalopathy present with somnolence or semi-stupor state, are confused and grossly disoriented, and have bizarre behavior.
Grade 4 is incorrect because patients with grade 4 hepatic encephalopathy present in a comatose state.
contingency management as it uses positive reinforcement to encourage abstinence from drugs.
Contingency management focuses on the maximal usage of medical clinic offices and guarantees decreased future hospitalizations.