Nucs agents CORE - Sheet1 Flashcards

1
Q

mechanism: MDP

A

phospate analog - chemisorption

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2
Q

mechanism: Free Xe-133

A

not absorbed (inspired) - can diffuse into fat

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3
Q

mechanism: MAA

A

albumin - gets stuck in capillary (10-100 microns)

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4
Q

mechanism: sulfur colloid

A

phagocytized by RES

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5
Q

mechanism: HIDA

A

bilirubin analog

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6
Q

mechanism: WBC

A

tagged neutrophil - goes to RES or active inflammation

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7
Q

mechanism: RBC

A

tagged RBC - circulated in blood

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8
Q

mechanism: MAG-3

A

actively secreted

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9
Q

mechanism: DMSA

A

binds to sulhydryl group in proximal tubule

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10
Q

mechanism: pertechnetate

A

active transport in thyroid

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11
Q

mechanism: free Ga-67

A

iron analog - taken up by bacteria and WBC

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12
Q

mechanism: FDG

A

glucose analog

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13
Q

mechanism: Sestamibi

A

active transport

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14
Q

mechanism: thallium 201

A

potassium analog, active transport (Na/K pump)

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15
Q

mechanism: pentreotide

A

analog of octreotide

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16
Q

mechanism: MIBG

A

analog of norepinephrine - enters neuroendocrine cells by active uptake mechanism via epinephrine transporter and is stored in neurosecretory granules

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17
Q

mechanism: HMPAO

A

lipophilic, cross BBB

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18
Q

mechanism: DTPA (cistern)

A

water soluble

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19
Q

mechanism: iodine

A

active transport in thyroid

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20
Q

normal distribution: MDP

A

bones, kidneys

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21
Q

normal distribution: Free Xe-133

A

airways

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22
Q

normal distribution:MAA

A

lungs

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23
Q

normal distribution: sulfur colloid

A

liver, spleen, bone marrow

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24
Q

normal distribution: HIDA

A

liver, GB, bowel

25
Q

normal distribution: WBC

A

spleen, liver, bone marrow

26
Q

normal distribution: RBC

A

blood pool

27
Q

normal distribution: MAG-3

A

kidneys, bladder

28
Q

normal distribution: DMSA

A

kidneys

29
Q

normal distribution: pertechnetate

A

stomach, salivary glands, thyroid

30
Q

normal distribution:free Ga-67

A

liver, lacrimal and salivary glands, bones, minimal lung

31
Q

normal distribution: FDG

A

brain, heart, liver, blood pool

32
Q

normal distribution: Sestamibi

A

salivary glands, GI tract, heart, kidneys, thyroid, parathyroid

33
Q

normal distribution: thallium 201

A

heart, kidneys

34
Q

normal distribution: pentreotide

A

spleen, liver, kidneys, bladder

35
Q

normal distribution:MIBG

A

thyroid, heart, liver, spleen, salivary glands

36
Q

normal distribution: HMPAO

A

brain, blood pool

37
Q

normal distribution:DTPA (cistern)

A

csf, kidney, bladder

38
Q

normal distribution: iodine

A

thyroid, nasopharynx, salivary glands, stomach, bowel, bladder

39
Q

critical organ: MDP

A

bladder

40
Q

critical organ: Free Xe-133

A

trachea/airways

41
Q

critical organ:MAA

A

lungs

42
Q

critical organ: sulfur colloid

A

proximal colon

43
Q

critical organ: HIDA

A

gallbladder wall

44
Q

critical organ: WBC

A

spleen

45
Q

critical organ: RBC

A

heart

46
Q

critical organ: MAG-3

A

bladder

47
Q

critical organ: DMSA

A

kidney

48
Q

critical organ: pertechnetate

A

stomach

49
Q

critical organ: free Ga-67

A

distal colon

50
Q

critical organ: FDG

A

bladder

51
Q

critical organ: Sestamibi

A

proximal colon

52
Q

critical organ: thallium 201

A

renal cortex

53
Q

critical organ: pentreotide

A

spleen

54
Q

critical organ:MIBG

A

spleen

55
Q

critical organ: HMPAO

A

bladder

56
Q

critical organ: DTPA (cistern)

A

spinal cord

57
Q

critical organ: iodine

A

thyroid

58
Q

proximal colon is the critical organ for these 2

A

sulfur colloid and sestamibi