Nucs agents CORE - Sheet1 Flashcards
mechanism: MDP
phospate analog - chemisorption
mechanism: Free Xe-133
not absorbed (inspired) - can diffuse into fat
mechanism: MAA
albumin - gets stuck in capillary (10-100 microns)
mechanism: sulfur colloid
phagocytized by RES
mechanism: HIDA
bilirubin analog
mechanism: WBC
tagged neutrophil - goes to RES or active inflammation
mechanism: RBC
tagged RBC - circulated in blood
mechanism: MAG-3
actively secreted
mechanism: DMSA
binds to sulhydryl group in proximal tubule
mechanism: pertechnetate
active transport in thyroid
mechanism: free Ga-67
iron analog - taken up by bacteria and WBC
mechanism: FDG
glucose analog
mechanism: Sestamibi
active transport
mechanism: thallium 201
potassium analog, active transport (Na/K pump)
mechanism: pentreotide
analog of octreotide
mechanism: MIBG
analog of norepinephrine - enters neuroendocrine cells by active uptake mechanism via epinephrine transporter and is stored in neurosecretory granules
mechanism: HMPAO
lipophilic, cross BBB
mechanism: DTPA (cistern)
water soluble
mechanism: iodine
active transport in thyroid
normal distribution: MDP
bones, kidneys
normal distribution: Free Xe-133
airways
normal distribution:MAA
lungs
normal distribution: sulfur colloid
liver, spleen, bone marrow
normal distribution: HIDA
liver, GB, bowel
normal distribution: WBC
spleen, liver, bone marrow
normal distribution: RBC
blood pool
normal distribution: MAG-3
kidneys, bladder
normal distribution: DMSA
kidneys
normal distribution: pertechnetate
stomach, salivary glands, thyroid
normal distribution:free Ga-67
liver, lacrimal and salivary glands, bones, minimal lung
normal distribution: FDG
brain, heart, liver, blood pool
normal distribution: Sestamibi
salivary glands, GI tract, heart, kidneys, thyroid, parathyroid
normal distribution: thallium 201
heart, kidneys
normal distribution: pentreotide
spleen, liver, kidneys, bladder
normal distribution:MIBG
thyroid, heart, liver, spleen, salivary glands
normal distribution: HMPAO
brain, blood pool
normal distribution:DTPA (cistern)
csf, kidney, bladder
normal distribution: iodine
thyroid, nasopharynx, salivary glands, stomach, bowel, bladder
critical organ: MDP
bladder
critical organ: Free Xe-133
trachea/airways
critical organ:MAA
lungs
critical organ: sulfur colloid
proximal colon
critical organ: HIDA
gallbladder wall
critical organ: WBC
spleen
critical organ: RBC
heart
critical organ: MAG-3
bladder
critical organ: DMSA
kidney
critical organ: pertechnetate
stomach
critical organ: free Ga-67
distal colon
critical organ: FDG
bladder
critical organ: Sestamibi
proximal colon
critical organ: thallium 201
renal cortex
critical organ: pentreotide
spleen
critical organ:MIBG
spleen
critical organ: HMPAO
bladder
critical organ: DTPA (cistern)
spinal cord
critical organ: iodine
thyroid
proximal colon is the critical organ for these 2
sulfur colloid and sestamibi