Nucleus

Question 1

Shape of nucleus of neuron?

Of muscle cell?

Answer 1

neuron - round

muscle - oval

Question 2

What does the nucleolus do?

Answer 2

makes ribosomes!

Question 3

What is a nucleosome?

Answer 3

DNA + histones

Question 4

How much DNA in chromatin codes for genes? Hb satellite DNA?

Answer 4

1% genes
3% satellite
45% made from transposons
rest junk

Question 5

Why do nuclei have a lot of variation?

Answer 5

B/c of variation in gene transcription

Question 6

Cells with a lot of _________ are transcribing a lot of genes

Answer 6

euchromatin

Question 7

what is chromatin?

Answer 7

DNA and associated proteins

Question 8

A chromosome is made up of

• middle part?
• end parts?

Answer 8

centromere

telomeres

Question 9

Chromosome assessment for abnormalities or issues is called what?

Answer 9

Karyotype analysis

Question 10

What stage of mitosis does chromo assessment take place?

Answer 10

Anaphase

microtubules are destabilized by drugs

Question 11

chromosomes in the _________ stage of mitosis occupy unique areas in the nucleus

Answer 11

Interphase

Question 12

What are the 4 stages of the cell cycle?

Answer 12

G1
S
G2
M

Question 13

What happens in G1 phase?

Answer 13

stabilization/G0 phase

Question 14

What happens in S phase?

Answer 14

chromo duplication & DNA synthesis @ many replication origin sites

Question 15

In s-phase, each attached chromo is termed a ______

Answer 15

chromatid

Question 16

What happens in G2 phase?

Answer 16

nothing

Question 17

what happens in M phase?

Answer 17

Each chromatid attaches to mitotic spindle which bind to kinetochore, which binds to DNA @ a centromere.

Question 18

what is the end result of M phase?

Answer 18

Chromatids are pulled apart and distributed into daughter cells.

Question 19

________ regulates DNA synthesis

Answer 19

Rb protein