Nucleus Flashcards
Size and structure
Largest organelle, surround by nuclear envelope, contain genetic info of cell (DNA + RNA)
Genetic info
DNA arranged as chromosomes
Coil around histone core
Nucleoproteins
+ve histones: control uncoiling/expression of genes, modified to promote/suppress gene expression
Non-histone proteins: enzymes for synthesis RNA/DNA and other regulatory proteins
Nuclear envelope
2 lipid bilayers w/ intermembranous space between, contains nuclear pores, regulate exchange of metabolites, macromolecules, ribosomal subunits (communication between nucleus and cytoplasm)
Defines eukaryotes
Nucleolus
Site of rRNA and ribosome assembly
Nuclear functions
Gene replication/repair, transcription, ribosome production, protect DNA
Control centre of cell
Heterochromatin
Electron dense areas
Tightly coiled, inactive chromatin
Constitutive = condensed throughout cell cycle/development, highly repetitive sequences not transcribed, role in chromosome structure
Facultative = regions of euchromatin convert to heterochromatin, potential for gene expression, condensed or loosen depending on cell type
Barr body
Inactive X chromosome in female somatic cells to regulate amount X-linked gene product transcribed
Facultative heterochromatin
Euchromatin
Electron lucent areas
Active DNA, act as template for RNA synthesis