Nucleic acids and Nucleotides Flashcards

1
Q

Nucleic acids

A

are long, linear polymers constructed from four types of monomers
Each monomer consists of a sugar, a phosphate, and a base.

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2
Q

Name the purines

A

adenine, guanine

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3
Q

Name the pyrimidines

A

cytosine, uracil, thymine

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4
Q

Semiconservative replication

A

the replication process to make two daughter helices from one parent strand and one newly synthesized strand

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5
Q

What is the most common type of structure DNA is seen?

A

B form or the Watson-Crick helix

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6
Q

Name the 3 types of DNA structures.

A

B form or the Watson-Crick helix, A form, which is shorter and wider than the B form with the bases at an angle rather than perpendicular to the helix axis and Z DNA

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7
Q

Nucleotide

A

a nucleoside with one or more phosphoryl groups attached

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8
Q

Nucleoside

A

a nitrogenous base bound to a sugar

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9
Q

What bases pair together and what kind of bond and how many of that bond do they have?

A

Hydrogen bonds- A with T, 2
G with C, 3

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10
Q

Chromatin

A

entire complement of a cell’s DNA and its associated proteins

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11
Q

Nucleosome

A

Two copies each of histones H2A, H2B, H3, H4 and 200 bp of DNA

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12
Q

What is Cisplatin

A

a chemotherapeutic agent that reacts with DNA such that nitrogens of adjacent purines replace the chloride atoms.

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13
Q

how sugars are attached to DNA and RNA

A

In all cases, the C-1’ of the sugar is aLached to the N-9 of the purine or the N-1 of the pyrimidine.

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