Nucleic acids Flashcards
What does the primary structure do
The primary structure determines is the subsequent high structures due to positioning of the amino acids
Secondary Structure
Primary structure folds due to positive and and negative charge on -C=0 group and N-H group in the peptide bond forming h- bonds.
Tertiary Structure-
It folding to a tertiary structure depends on the arrangement of amino acids which lead to the formation ionic bonds and disulfide bridges.
Quaternary Structure
two or more polypeptides
Properties of enzymes
- Globular tertiary structures
- Act as biological catalysts
- Never used up in a reaction
Activation energy
Energy required to break existing bonds
Needed to stop repulsion between reacting molecules
By holding substrate in active site, the reduce repulsion and activation energy
Specific
Enzyme is complementary to the substrate
Lock and key
Substrate complementary active site
fit together
Undergo catalysis
Induced fit theory
During E-S formation, a small change occurs on the conformational shape of the protein. Co factors as well affect whether an active site is induced.