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8.5 NSAIDS PART 2 > NSAIDS PART 2 > Flashcards

NSAIDS PART 2 Flashcards

1
Q

which is the correct comparison of dosages for aspirin?

a. antiplatelet > anti-inflammatory
b. antiplatelet < antipyresis
c. anti-inflammatory < antipyresis
d. antipyresis > analgesic

A

antiplatelet < antipyresis / analgesic < anti-inflammatory

80-160 , 160-325, 325-650 mg

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2
Q

which two aspirin dosages are equal??

a. antiplatelet and analgesic
b. antiplatelet and antipyretic
c. anti-inflammatory and analgesic
d. analgesic and antipyretic
e. none of the above

A

antipyretic = analgesic

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3
Q

Which is a salicylate-like NSAID and a COX2 inhibitor?

a. ketorolac
b. celebrex
c. ibuprofen

A

celebrex is a COX2 inhibitor!

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4
Q

salicyclate-like NSAID’s with the suffix “coxib” are all inhibitors of what?

a. COX1
b. COX2

A

coxib = COX2 inhibitors

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5
Q

ketorolac is least COX2 selective while rofecoxib is most COX2 selective

A

true

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6
Q

which has the longest plasma half-life?

a. ketorolac
b. celecoxib
c. ibuprofen
d. piroxicam

A

piroxicam

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7
Q

ibuprofen is least GI toxic while piroxicam is most GI toxic.

A

true

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8
Q

for plasma half life, acetaminophen < aspirin < ibuprofen < ketorolac < celecoxib

A

TRUE! acetaminophen has shortest half life compared to the others.

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9
Q

Which can elevate IOP, cause cataracts, cause HPA axis effects, and has risk of post-op cystoid macular edema?

a. NSAIDs
b. Steroids

A

Steroids

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10
Q

Which has “ceiling effect” (maximum limit of analgesia regardless of dose)?

a. NSAIDs
b. OPIOIDS

A

NSAIDs

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11
Q

All of the following are true statements, except:

a. Opioids have no ceiling effect.
b. NSAIDs cause mydriasis
c. NSAIDs are non-addictive while Opioids are addictive.
d. Opioids have topicals available.
e. NSAIDs are for anti- inflam, anti-platelet and anti-pyresis; Opioids are NOT for anti-inflam, antipyretic, anti-platelet.

A

Opioids do not have topical form. only non-topical!

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12
Q

which is for peripheral pain?

a. acetaminophen
b. aspirin

A

aspirin

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13
Q

which is safe in pregnant women?

a. acetaminophen
b. aspirin

A

acetaminophen (tylenol) is safe in pregnant women

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14
Q

is acetaminophen anti-inflammatory and anti-platelet?

A

no, it is not because it is NOT an NSAID.

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15
Q

what is the treatment plan for a patient who overdoses on aspirin?

A

dialysis!

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16
Q

All of the following describe “Reye’s Syndrome”, except:

a. adverse reaction in children taking aspirin to reduce fever in a bacterial infection.
b. causes GI disturbances and liver degeneration.
c. can cause encephalopathy.
d. mortality rate is 35%

A

a is false. it affects the treatment of VIRAL infections such as chicken pox or influenza

17
Q

when children have fevers, they should take tylenol or ibuprofen, instead of aspirin.

A

true

18
Q

which is not true of aspirin?

a. anti inflammatory
b. anti platelet
c. not good for pregnant women
d. no GI effects
e. none of the above

A

no GI effects is false!!! aspirin does cause GI disturbances.

19
Q

aspirin is eliminated in the liver; tylenol is eliminated in the kidney.

A

false! the other way around.

aspirin –> kidney (that’s why dialysis is the treatment if overdose on aspirin).

20
Q

NSAIDs can interact with:

a. other NSAIDs
b. steroids
c. anticoagulants
d. omega 3
e. gingko biloba
f. all of the above

A

all of the above!

21
Q

if patient is taking beta blockers for glaucoma, is it safer to take aspirin or acetaminophen?

A

don’t give aspirin!

22
Q

which topical NSAID is most prescribed to treat allergic conjunctivitis (AC)?

a. flurbiprofen
b. ketorolac
c. diclofenac
d. bromfenac

A

ketorolac!!!

23
Q

cyclosporine-A is the first immunosuppressant on the market to treat _______.

A

dry eye

24
Q

cyclosporine-A is also called __________.

A

Restasis

25
Q

cyclosporine-A (restasis) reversibly reduces pro-inflammatory T-helper cell cytokines, such as IL-2, IL-4, IFN-gamma, and TNFa, as well as inhibits mast cell degranulation.

A

true

26
Q

cyclosporine-A is contraindicated against patients with active ocular infection, or known hypersensitivity.

A

true

27
Q

cyclosporine-A is preservative free

A

true

8.5 NSAIDS PART 2 (1 decks)

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