NSAIDS And Non Narcotics 2

Question 1

Third line agents against neuropathic pain? 4?

Answer 1

NMDA antagonists, combination of analgesics, TB

Question 2

What are the two 4th line agents against neuropathic pain?

Answer 2

Botox injection

Intrathecal ziconotide

Question 3

MOS of ketamine?
2 clinical indications?
What is the general umbrella of side effects?

Answer 3

NDMA antagonist
Start and maintain anesthesia and post op pain
Psychological reactions

Question 4

MOA of dexmedetomidine?

2 clinical uses?

Answer 4

Alpha 2 adrenergic agonist

Pain and sedation

Question 5

MOA of clonidine?

2 clinical uses?

Answer 5

Alpha 2 adrenergic agonist

HTN and severe pain

Question 6

MOA for ziconotide?

Clinical indication?

Answer 6

antagonist to N type voltage sensitive calcium channels

Chronic severe pain for those who warrant an inrathecal administration when other treatments don’t work.

Question 7

MOA of Capsaicin?
MOA of Camphor?
MOA of menthol?
MOA of aspercreme with lidocaine?

Answer 7

Stimulates TRPV1 that blocks substance P
Blocks TRPV1
Stimulates TRPM8 which causes cool sensation
Topical NSAID with sodium channel blocker