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Chapter 15 Rheumatological > NSAIDs > Flashcards

NSAIDs Flashcards

1
Q 
Diclofenac (Voltaren)
Ibuprofen (Nurofen)
Indomethacin (Arthrexin)
Ketoprofen (Orudis SR)
Ketorolac (Toradol)
Mefenamic acid (Ponstan)
Naproxen (Naprosyn OR Proxen)
Piroxicam (Feldene)
A

A) Non-selective NSAIDs

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2
Q

Celecoxib (Celebrex)
Meloxicam (Movalis)
Parecoxib

A

A) Selective COX-2 inhibitor NSAID

B)

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3
Q

Diclofenac (Voltaren)

A

A) Non-selective NSAID

B)

  1. Rheumatoid Arthritis
  2. Osteoarthritis
  3. Pain (inflammation)
  4. Heavy Menstrual Bleeding
  5. Actinic Keratoses

C)
75-200 mg daily (in 2 or 3 doses)

D)

  1. AMINOTRANSFERASE conc.**
  2. Asthma
  3. Renal
  4. Cardiovascular disease (HF and HTN may worsen)
  5. BP.
  6. G.I. bleed
  7. Complete BLOOD Count (Chronic)
  8. Haemoglobin (Chronic)
  9. Pain score
  10. Liver

E)
Labels: 10a, 12+, 19b, A*, B
#Can increase the risk of heart attack or stroke
#Safe to take paracetamol
#Don’t take if you are dehydrated (increase side effects)
**DR - (IBD) new or unusual ABDO pain or tenderness, indigestion or heartburn
**DR - allergic reaction
**DR - (internal bleed) dark or blood stained bowel motions coffee coloured vomit
S/E
*GIT (nausea and dyspepsia, GI ulceration or bleeding)
*CNS (headache, dizziness)

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4
Q

Ibuprofen (Nurofen)

A

A) Non-selective NSAID

B)

  1. RA
  2. OA
  3. Pain (inflammation)
  4. Fever
  5. Heavy Menstrual Bleeding

C)
200-400 mg TDS or QID
Max 2.4g daily

D)

  1. Clinical improvement (i.e. fever)
  2. Asthma
  3. Renal
  4. Cardiovascular disease (HF and HTN may worsen)
  5. BP.
  6. G.I. bleed
  7. Complete BLOOD Count (Chronic)
  8. Haemoglobin (Chronic)
  9. Pain score
  10. Liver

E)
Labels: 10a, 12+, 19b, B
#Take with WATER. It may be taken without food, but if this upsets your stomach, try taking it with a meal
#Can increase the risk of heart attack or stroke
#Safe to take paracetamol
#Don’t take if you are dehydrated (increase side effects)
**DR - (IBD) new or unusual ABDO pain or tenderness, indigestion or heartburn
**DR - allergic reaction
**DR - (internal bleed) dark or blood stained bowel motions coffee coloured vomit
S/E
*GIT (nausea and dyspepsia, GI ulceration or bleeding)
*CNS (headache, dizziness)

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5
Q

Indomethacin (Arthrexin)

A

A) Nonselective NSAID

B)

  1. RA
  2. OA
  3. Ankylosing Spondylitis
  4. Acute Gout
  5. Pain (inflammation)

C)
25-50 mg BD-QID daily

D)

  1. Proctitis
  2. Asthma
  3. Renal
  4. Cardiovascular disease (HF and HTN may worsen)
  5. BP.
  6. G.I. bleed
  7. Complete BLOOD Count (Chronic)
  8. Haemoglobin (Chronic)
  9. Pain score
  10. Liver

E)
Labels: 10a, 12+ 19b, A*, B
#Take capsules WITH or shortly after FOOD
#Can increase the risk of heart attack or stroke
#Safe to take paracetamol
#Don’t take if you are dehydrated (increase side effects)
**DR - (IBD) new or unusual ABDO pain or tenderness, indigestion or heartburn
**DR - allergic reaction
**DR - (internal bleed) dark or blood stained bowel motions coffee coloured vomit
S/E
*GIT (nausea and dyspepsia, GI ulceration or bleeding)
*CNS (headache, dizziness)

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6
Q

Ketoprofen (Orudis SR)

A

A) Nonselective NSAID

B)

  1. RA
  2. OA

C)

oral: 200mg ONCE daily
rectal: 100 mg at bedtime

D)

  1. Proctitis
  2. Asthma
  3. Renal
  4. Cardiovascular disease (HF and HTN may worsen)
  5. BP.
  6. G.I. bleed
  7. Complete BLOOD Count (Chronic)
  8. Haemoglobin (Chronic)
  9. Pain score
  10. Liver

E)
Labels: 10a, 12+ 19b, A*, B
#Take capsules WITH or shortly after FOOD
#Can increase the risk of heart attack or stroke
#Safe to take paracetamol
#Don’t take if you are dehydrated (increase side effects)
**DR - (IBD) new or unusual ABDO pain or tenderness, indigestion or heartburn
**DR - allergic reaction
**DR - (internal bleed) dark or blood stained bowel motions coffee coloured vomit
S/E
*GIT (nausea and dyspepsia, GI ulceration or bleeding)
*CNS (headache, dizziness)

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7
Q

Ketorolac (Toradol)

A

A) Nonselective NSAID

B)
1. Mild-Mod. POST-OP. pain

C)
10mg (every 6-8 hrs)
Max 40mg daily

D)

  1. Dehydration or Hypovolaemia
  2. Asthma
  3. Renal
  4. Cardiovascular disease (HF and HTN may worsen)
  5. BP.
  6. G.I. bleed
  7. Complete BLOOD Count (Chronic)
  8. Haemoglobin (Chronic)
  9. Pain score
  10. Liver

E)
Labels: 10a, 12+ 19b, A*, B
#Can increase the risk of heart attack or stroke
#Safe to take paracetamol
#Don’t take if you are dehydrated (increase side effects)
**DR - (IBD) new or unusual ABDO pain or tenderness, indigestion or heartburn
**DR - allergic reaction
**DR - (internal bleed) dark or blood stained bowel motions coffee coloured vomit
S/E
*GIT (nausea and dyspepsia, GI ulceration or bleeding)
*CNS (headache, dizziness)

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8
Q

Mefenamic Acid (Ponstan)

A

A) Nonselective NSAID

B)

  1. Pain (inflammation)
  2. Heavy Menstrual Bleeding

C)
500 mg TDS

D) Same

E)
Labels: 10a, 12+, 19b, B

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9
Q

Naproxen (Naprosyn)

A

A) Nonselective NSAID

B)

  1. RA
  2. OA
  3. Ankylosing sponylitis
  4. Pain (inflammation)
  5. Heavy Menstrual Bleeding

C)
IR: 250-500mg BD
CR: 750-1000mg ONCE
Max: 1250mg

Period pain: 500mg stat, 250mg every 6-8hrs
Migraine: 750mg stat, 250-500mg at least 1 hr after

D)
Same

E)
Labels: 10a, 12+, 19b, A*, B
#Can increase the risk of heart attack or stroke
#Safe to take paracetamol
#Don’t take if you are dehydrated (increase side effects)
**DR - (IBD) new or unusual ABDO pain or tenderness, indigestion or heartburn
**DR - allergic reaction
**DR - (internal bleed) dark or blood stained bowel motions coffee coloured vomit
S/E
*GIT (nausea and dyspepsia, GI ulceration or bleeding)
*CNS (headache, dizziness)

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Chapter 15 Rheumatological (3 decks)

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