NSAIDS

Question 1

selective COX2 inhibitor
doesn’t block COX 1–particularly in stomach
AE: suppresses prostacyclin, increasing risk for thrombosis

Answer 1

Celecoxib

Question 2

blocks COX in the CNS but not the periphery
NOT antiinflammatory
good anti-pyretic and analgesic

Answer 2

Acetominophen (Tylenol)

Question 3

Irreversible inhibitor of COX
eliminates platelet production of thromboxane A2 for life of cell bc no nucleus to produce more
used to eliminate thrombosis (especially in MI)

Answer 3

Acetylsalycylic acid (Aspirin)

Question 4

non selective, reversible COX inhibitors

Answer 4

Ibuprofen
Naproxen (Aleve)- longer acting