NSAID use Flashcards

1
Q

Tylenol dosage

A

650 mg ever 4-6 hours, max 4g

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2
Q

Aspirin dosage

A

650 mg every 4 hours, max 4 g

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3
Q

ibuprofen dosage

A

200-400 mg every 4-6 hours, max 1200 mg

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4
Q

naproxen dosage

A

220 mg ever 8-12 hours, max 660 mg

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5
Q

acetaminophen considerations in elder

A

use <3g per day

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6
Q

acetaminophen renal considerations

A
  • GFR 10-50 dose q6h

- GFR <10 dose q8h

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7
Q

aspirin renal/hepatic considerations

A

avoid if GFR <10 or severe liver disease

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8
Q

ibuprofen renal considerations

A

avoid if eGFR <60

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9
Q

naproxen renal considerations

A

avoid if CrCl <30

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10
Q

contraindications for otc pain treatment

A
  • mod to severe
  • last >10 days
  • increases intensity
  • back pain and loss of bowel/bladder control
  • accompanying N/V/fever
  • 3rd tri of pregnancy
  • history of liver disease
  • signs of injury
  • deformed joint, abnormal movement
  • <2 years old
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11
Q

acetaminophen uses

A

analgesic

antipyretic

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12
Q

acetaminophen preferred populations to use in

A
  • anticoagulat medications
  • aspirin allergy
  • children with fever
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13
Q

acetaminophen side effects

A

rash, hepatotoxicity, renal failure in high chronic doses

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14
Q

acetaminophen drug interactions

A

warfarin
alcohol
cholestyramine

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15
Q

NSAID uses

A

analgesic
anti-inflammatory
antipyretic

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16
Q

NSAIDs side effects

A

N/V/D, dyspepsia, rash, dizziness

17
Q

NSAID drug interactions

A
  • ACEi
  • ARB
  • diuretics
  • anticoagulants
  • SSRI
  • corticosteroids
18
Q

contraindications of NSAIDs

A
  • active peptic ulcer
  • GI bleed
  • Hx of ulcers
  • 3rd trimester of pregnancy
19
Q

misoprostol use

A

help prevent ulcerations when using NSAIDs/COX-2i

20
Q

misoprostol contraindication

A

pregnancy

21
Q

misoprostol side effects

A

diarrhea

abdominal pain

22
Q

signs of hepatotoxicity

A
  • nausea
  • fatigue
  • lethargy
  • jaundice
  • upper right quadrant pain
23
Q

when to notify clinicians about pts on NSAIDs

A
  • suspected pregnancy
  • sign of GI toxicity
  • sign of hepatotoxicity
24
Q

aspirin side effects

A

nausea, vomiting, anti-platelet effect, decreased urate excretion

25
Q

aspirin drug interactions

A
  • NSAIDs
  • alcohol
  • ACEi
  • beta blockers
  • anti-platelets
26
Q

asprin contraindications

A
  • salicylate allergy
  • asthma
  • rhinitis
  • nasal polyps