NSAID

Question 1

What NSAIDs are used for dental or orofacial pain

Answer 1

Ibuprofen, diclofenac sodium/potassium

Question 2

At what CrcL should naproxen be avoided?

Answer 2

30L/Min

Question 3

When should NSAIDs be avoided in the elderly?

Answer 3

Antiplatelet/anticoagulant

Concurrent antiplatelet without PPI

EGFR <50mL/Min

Severe hypertension or HF

COX-2 with concurrent CVD

Question 4

What NSAID has an increased risk of CVD?

Answer 4

COX-2, diclofenac (150mg daily) and ibuprofen (2.4g daily), aceclofenac (but limited evidence) ,

Diclofenac and etoricoxib= similar risk

Question 5

What NSAID has an lowest risk of CVD?

Answer 5

Naproxen (1g daily) and ibuprofen (1.2g daily or less)

Question 6

What NSAID has the highest risk of GI events?

Answer 6

Piroxicam, ketoprofen, ketorolac trometamol

Question 7

What NSAID has an intermediate risk of GI events?

Answer 7

Indometacin, Diclofenac, naproxen

Question 8

What NSAID has the lowest risk of GI events?

Answer 8

Ibuprofen, COX-2.