nRBC Flashcards

1
Q

Where can all stages of nRBCs be found?

A

in the bone marrow

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2
Q

which nRBCs can occasionally be found in peripheral blood?

A
  1. metarubricytes
  2. rubricytes
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3
Q

what might normally be seen with regenerative anemia?

A

increased nRBCs

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4
Q

when is anemia considered regenerative?

A

if reticulocytes are present

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5
Q

to confirm adequate bone marrow response in anemic animals what should be counted? (2)

A
  1. reticulocytes
  2. nRBCs
    want the ratio to be greater than 1
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6
Q

what does nRBCs outnumbering reticulocytes indicate?

A

an inappropriate response

nRBCs commonly outnumber them due to bone marrow damage

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7
Q

increase number of nRBCs may be an appropriate response to what?

A

increased erythropoiesis due to regenerative anemia

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8
Q

What can cause bone marrow damage? (6)

A
  • necrosis
  • inflammation
  • endotoxemia
  • hypoxia
  • myelodysplasia
  • neoplasia
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9
Q

causes of inappropriately increased nRBC (5)

A
  1. lead poisoning
  2. extramedullary cell production
  3. altered splenic function (splenectomy)
  4. corticosteroids
  5. trauma
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10
Q

nRBC normals /100 WBC

A

0-2

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11
Q

what species are nRBCs rarely seen in? (4)

A

horses
cows
goats
sheep

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12
Q

adjust WBC count if nRBC count is

A

5 or more

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13
Q

what effect may nRBCs have on an analyzer WBC count

A

will increase the WBC count falsely

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14
Q

when do you correct the WBC count?

A

if nRBCs are greater than or equal to 5

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