Notes From Lorenzo's Oil

Question 0

What Changes were apparent in Lorenzo’s family?

Answer 0

1. Their lives were dominated to seeking a cure

2. They wanted to find unconventional treatment

Question 1

In the Movie, What Did the doctors try first in the Trial Studies?

Answer 1

1. Change the diet (high carb, low fat)

2. Immunosuppressive therapy (chemotherapy)

Question 2

What is the Significance of the Polish Rats?

Answer 2

1. Diet modification could lower certain fat levels

- Fatty acid manipulation

Question 3

What were the Oils?

Answer 3

1. Oleic Acid (olive oil)

2. Erusic Acid (Rape Seed Oil)

Question 4

How was the Oil administered?

Answer 4

1. Through the NG tube

Question 5

What were the oils made from?

Answer 5

1. Rape seed extract taken from Canola

2. Oleic acid is taken from olive oil

Question 6

What is the Inheritance Pattern?

Answer 6

1. The disease goes from Mother to Son

- The mother is the carrier but it is only expressed in Males

Question 7

How did Lorenzo Improve after the Oil

Answer 7

1. He didn’t need suctioning
2. No seizures
3. Breathing was improved
4. He was able to communicate through blinking

Question 8

At the end of the movie, Lorenzo’s dad gets an idea for a cure from what?

Answer 8

1. The puppies

Question 9

Who is the Lorenzo’s Rat?

Answer 9

1. His aunt DD who was also a carrier of the disease

Question 10

Why Could the oil be tested on the aunt?

Answer 10

1. She was also a carrier of the disease

Question 11

What did the Spigits (sink) represent?

Answer 11

1. The spigit was the intake of LONG CHAIN FATTY ACIDS

Question 12

What did the drain represent?

Answer 12

1. The enzymes that break down the long chain fatty acids

Question 13

What diet was Lorenzo placed on?

Answer 13

1. Anything that restricted the long-chain fatty acids

Question 14

What do the paperclips represent

Answer 14

1. Carbon chains