Notes Flashcards
ARTHRITIDES
= Arthritic conditions
Over 100 different conditions
4 Categories
- Inflammatory
- Degenerative
- Metabolic
- Infection
Inflammatory Arthritides
Characteristics:
- Soft tissue swelling, edema
- Uniform loss of joint space
- Erosions
- Cystic changes: juxta-articular osteoporosis/osteopenia
- Monoarticular or polyarticular
- Symmetric pattern
- Greater predisposition to fusion (ankylosis) than degenerative or metabolic
- Ex: Rheumatoid
Degenerative Arthritides
Characteristics:
- Non-uniform loss of joint space
- Osteophytes
- Subchondral clerosis
- Cystic changes
- Asymmetric changes
Metabolic Arthritides
characteristics:
- Notable soft tissue masses within periarticular soft tissues
- Well-marginated bone lesions
- Relative preservation of joint space
- Overlapping degenerative and inflammatory changes is common
- “The lumpy bumpy arthritis”
- ex: gout
Infectious/Septic Arthritis
- Common cause of grossly destroyed and disintegrated joints
- Gereatest incidence is below age 30
- Monoarticular is most common
- Caused by blood borne pathogens and direct implantation (S. aureus is most common organism)
Radiological Assessment of Joints (I)
Plain film shows bone involvement, therefore hard to detect early disease.
Radiological Assessment of Joints (II)
Radiolographic findings lag behind clinical: 30-50% of bone must be destroyed to see it on x-ray, 3% to see on bone scan (= radionuclide scintigraphy).
Radiological Assessment of Joints (III)
Parameters:
- Clinical evaluation
- Age and sex
- Distribution of joint disease
- Readiographic appearance
- Lab tests
- Specialized imaging exams
General Age of Onset
0-20 Juvenile rheumatoid arthritis or other juvenile arthritis
20-40 Seronegative, seropositive joint disease/spondyloarthropathy
over 40 degenerative, DISH, gout, CPPD
ABCDS of Joint Diseases
Alignment Bone Cartilage (joint space) Distribution (consider target joints) Soft Tissues
Law of Parsimony
Taking historical points and physical findings and putting them together into one diagnosis
but patients often have more than one arthropathy.
ABCDS of Joint Diseases
Alignment Bone Cartilage (joint space) Distribution (consider target joints) Soft Tissues
DEGENERATIVE ARTHRITIS
Target joints are weight-bearing articulations of the: spine -hips -knee -AC joint -1st MTP -1st MC-trapezium -DIP joints
DEGENERATIVE ARTHRITIS
Although any joint can be affected) characteristics: - insidious onset - intermittent exacerbaions - aching pain, stiffness - aggravation of symptoms with environmental changes such as cold and drop in barometric pressure
Primary DJD
No evidence of underlying etiology
Secondary DJD
Caused by:
Abnormal forces including obesity, trauma, joint deformity
-Pre-existing cartilage pathology such as rheumatoid arthritis, fractures and meniscal damage
-Collapse of subchondral bone, such as avascular necrosis and osteoporosis
DJD Other names
Osteoarthritis Osteoarthritis Degenerative joint disease Degenerative disc disease Spondylosis Arthritis Arthrosis Kellgren’s arthritis
DJD Risk Factors
- Increases with age
- Females have increase in DJD of hands, kness
- Obesity increases DJD of knees and hips
- Trauma – most significan local factor
- High impact physical activity increases risk
- Increases with inactivity or excessive activity
DJD Clinical Features
- Poor radiographic-to-clinical correlation
- Stiffness, especially with rest
- Normal blood work
- Spinal stenosis
- Vertebrobasilar ischemia
DJD Progression/Development
Abnormal articular forces promote loss of chondroitin sulfate and interfere with normal chondrocyte function, which leads to:
- Cartilage degradation—fissures, flaking, vascularization
- Denudation process secondary to altered joint function
- Synovium hypertrophy
- Cartilaginous debris
- Osteophytes develop from cartilage metaplasia and increased capsular insertion stresses
DJD Radiology Features (I)
Enthesopathy = pathological osseous proliferation at tendon or ligament insertion; degenerative, inflammatory [enthuses=anatomical location of insertion of ligament/tendon into bone via Sharpey’s fibers]
Ankylosis (rare, but joint may look fused)
DJD Radiology Features (II)
Asymmetric distribution Asymmetric loss of joint space Osteophytes at joint margin Subchondral sclerosis Subchondral cysts (geodes) Subluxation Interarticular loose bodies