Notes 19 Flashcards
Cancer kills 1 in every __ ppl
6
how are tumors produced
normal regulators of cell proliferation are lost, cell divides rapidly and produces tumor
benign
a tumor that stays in original tissue
Maligant
a tumor/ tumor cell that can invade healthy tissues and undergo mitosis
what can induce cancer
DNA viruses and retroviruses
transformation
Viral genome is integrated into host DNA
Proto-oncogenes
normally promote cell growth; when mutated they are excessively active in growth promotion
Tumor-suppressor genes
normally inhibit growth; when mutated cause inappropriate cell division
genome maintance gene
maintains genome integrity; when mutated results in deregulation of cell growth& proliferation = cancer