Nose and Sinus Flashcards
What is the most frequent acute illness in the US?
URI
How many URI episodes do preschool children have per. year?
5-7
How many URI episodes do adults have per. year?
2-3
What virus is the most common cause for the common cold?
Rhinovirus
Transmission of the common cold
- Respiratory droplets
2. Direct contact
Incubation period of the common cold
2-3 days
Typical duration of the common cold
3-10 days
Day 1 sx’s of the common cold
Sore throat
Day 2-3 sx’s of the common cold
Nose sx’s, congestion, drainage
Day 4-5 sx’s of the common cold
Cough
Why should you to discontinue Nasal Decongestant Spray (Afrin) after 3 days?
To avoid rebound congestion
Why do you want to use antihistamines (Diphenhydramine) with a decongestant with a common cold?
to avoid drying out
What is the most common cause of acute rhinosinusitis?
Viral: Rhinovirus, influenza, parainfluenza
What are some ref flags with acute rhinosinusitis?
- Fever >102 with severe HA
- Abnormal vision, EOM, proptosis, papilledema
- AMS
- CN palsies
- Meningeal signs
When would a CT with contrast be indicated for acute rhinosinusitis?
Suspected complicated acute bacterial rhinosinusitis (ABRS)
What imaging study would you order for recurrent or treatment resistant sinusitis?
Noncontrast CT
Features of bacterial cause
- Persistent signs or sx’s lasting 10 or more days
- Onset with severe sx’s lasting @ least 3 consecutive days @ beginning of illness
- “Double-worsening”
Acute rhinosinusitis treatment days 1-9?
Supportive care
Acute rhinosinusitis abx treatment?
Amoxicillin-clavulanate (Augmentin) x5-7 days
When would you give a high dose (2 g PO BID) of Amoxicillin-clavulanate for the treatment of Acute rhinosinusitis?
- > 65 y/o
- Recent hospitalization
- Antibiotic tx in past month
- Immunocompromised
- S. pneumo penicillin resistance > 10%
What abx are NOT recommended in the treatment of Acute rhinosinusitis?
- Macrolides
- Trimethoprim-sulfamethoxazole (Bactrim)
- 2nd or 3rd generation cephalosporins
Indications for referral for urgent endoscopy or surgical biopsy in acute rhinosinusitis?
- Fungal sinusitis or granulomatous disease is suspected
- Failure to respond to 1st and 2nd line antimicrobial tx
+ other obvious reasons listed
Complicated of acute rhinosinusitis?
- Periorbital or orbital cellulitis
- Meningitis
- Osteomyelitis of sinus bone
- Intracranial abscess
What is the number one risk factor for chronic rhinosinusitis?
Allergic rhinitis
chronic rhinosinusitis Ddx?
- Trigeminal neuralgia
- Migraines, HA’s
- Recurrent, acute rhinosinusitis
- Allergic rhinitis
Chronic rhinosinusitis supportive care treatments
- Nasal irrigation
- intranasal glucocorticoids
- Topical/oral antimicrobials
- Oral glucocorticoids
- Antileukotriene agents
Surgical Treatment in chronic rhinosinusitis if the patient can’t manage the sx’s
Endoscopic sinus surgery
Risk factors for allergic rhinitis?
- Early use of abx
- First born
- Male sex
- Birth during pollen season
- Presence of allergen-specific IgE
Intermittent allergic rhinitis classification
< 4 days/week OR < 4 weeks
Persistent allergic rhinitis classification
> 4 days/week AND >4 weeks
Moderate-severe allergic rhinitis
- Sleep disturbance
- Impaired school/work performance
- Impaired daily activities, leisure, and/or sport activities
- Troublesome sx’s
Perennial allergic rhinitis
Year round sx’s
Allergic Rhinitis physical exam findings
- “Allergic Shiners”
- “Allergic salute”
- “Cobblestoning”- hyperplastic lymphoid tissue in pos. pharynx
- Pale, bluish nasal mucosa
- Clear rhinorrhea
- TM retractions or serous fluid behind TM
What is the most common allergy skin test?
Prick skin test
-Given serum with allergen, trigger mast cels if sensitivity there
What is the most sensitive skin test?
Intradermal skin test
What do you want to remember to do with allergy skin testing?
Discontinue medications as they may interfere with testing/results
What is the benefit of a serum IgE for specific allergens?
- DONT have to stop meds
- Geographic panel
Allergic Rhinitis medication options
- Glucocorticoid + antihistamine nasal spray
- Oral Antihistamines-2nd or 3rd generation (Claritin, Allegra, Zyrtec)
- Nasal decongestant sprays
- Mast cell stabilizer
Nonallergic/Vasomotor Rhinitis etiology
- Abnormal autonomic regulation of innervation of nose
- Nasal eosinophilia without allergen sensitivity
Nonallergic/Vasomotor Rhinitis triggers
- Temperature changes-Humidity
- Eating-Hot or spicy
- Exposure to odors/chemicals
- Alcohol use
What is the first line treatment of nonallergic/vasomotor rhinitis?
Topical intranasal glucocorticoids
What is the most common cause of Epistaxis?
Nasal trauma-Nose picking
If someone is having a severe bleed, what lab would you order?
Hematocrit: Type and crossmatch
Conservative treatment for epistaxis
Occlusion, continuous x 10-15 minutes
Samter triad
Nasal Polyps +Asthma= Avoid Aspirin
-Immunologic salicylate sensitivity causes severe episode of bronchospasm
Nasal polyps treatment
Topical intranasal corticosteroids
Malignant neoplasms
Squamous cell carcinoma
Adenocarcinoma
Presentation of malignant neoplasms
Obstruction + Epistaxis