Nose Flashcards
What are the longterm complications of endoscopic ligation of the sphenopalatine artery?
Continued bleeding
CSF leak
visual disturbance
What area is supplied by the sphenopalatine artery?
lateral wall of the nose
What tests can be carried out in allergic rhinitis?
Either skin prick tests or RAST tests
Which type of hypersensitivity is involved in allergic rhinits?
type 1 (IgE)
What are potential treatments for allergic rhinits?
leukotriene receptor antagonists
corticosteroids
allergen avoidance
antihistamines
Antihistamines in allergy target what receptor?
H1 (H2 for GI)
What is the MOA of corticosteroids in allergy?
Glucocorticoids bind to intracytoplasmic glucocorticoid receptors which translocate into the cell nucleus and regulate gene expression to down-regulate production of inflammatory mediators.