Normal L&D Flashcards
When does beta-HCG peak?
10 weeks gestation
When can a pregnancy first be detected by ultrasound? What do you see?
TRANSVAGINAL- 5 weeks. Gestational sac but no heart until 6 weeks.
Beta-HCG level for TV U/S detection? Abdominal
1500 to 2000
Abdominal needs >6500
First trimester
up to 12 wks
Second trimester
12 wks to 24 wks
Third trimester
24 wks (or 28) to delivery
PreVIABLE delivery?
Before 24 wks
What EXACTLY does parity mean?
A pregnancy that led to a birth at or beyond 20 wks OR of an infant weighing more than 500g
Given birth to a set of twins?
G1P1 (it is considered ONE pregnancy)
The order of #s in GP….
pregnancies/#births at TERM/#births at PREterm/abortuses/living kids
What changes occur in the cardiovascular system during pregnancy?
1) CO inc by 30-50% (max at 20-24 wks then maintained)
2) Systemic vascular resistance decreases
3) BP drops and nadirs at 24 weeks then rises
Changes in pulm system during pregnancy?
1) Tidal volume inc
2) Respiratory rate UNCHANGED…therefore the combo increases MINUTE VENTILATION which inc O2 levels overall
3) Dyspnea of pregnancy
Changes in GI system in pregnancy?
Morning sickness…hyperemesis gravidarum
Prolonged gastric emptying time so GERD sx
Large bowel has dec motility so constipation
Hyperemesis gravidarum?
Severe morning sickness= WEIGHT LOSS & KETOSIS.
Renal system in pregnancy?
1) Kidneys get bigger
2) Ureters dilate
3) GFR inc by 50% early in pregnancy
4) Therefore BUN and creatinine dec
5) RAAS system inc (but sodium levels DON’T inc bc of the concomitant inc in GFR)
Hematologic changes in pregnancy?
1) Plasma volume increases more than hematocrit (RBCs) so there’s a DILUTIONAL ANEMIA
2) WBC count inc (range of 6-16 million). During stress of labor may rise to 20 million.
3) Platelets drop beta 100-150million/mL. (Greater drop INVESTIGATE IMMEDIATELY)
4) Hypercoagulability due to inc in fibrinogen, factors VII-X; clotting and bleeding TIMES don’t change
Endocrine changes in pregnancy?
1) Hyperestrogenic state
2) Alpha subunit of beta-HCG mimics LH, FSH, and TSH; peak at 10-12 wks
3) hPL inc (produced by placenta). Induces lipolysis with a concomitant inc in free fatty acids; also is insulin antagonist
4) Prolactin LEVELS inc but it doesn’t do anything until after birth of baby
5) Estrogen stims TBG, so there’s an inc in TOTAL T3 and T4 but FREE T3/T4 remain constant.
Calorie intake req during preg?
300kcal/day for preg; 500 kcal/day for breastfeeding
Weight gains
Underweight= 28-40lbs Normal= 20-30lbs Overweight= 15-25lbs
Folate req
0.4-0.8mg/day (Previous NTD or inc risk is 4mg/day)
Urinalysis in pregnancy looks for what?
Protein- preeclampsia
Glucose- diabetes
Leukocyte esterase- UTI
What are pregnant patients asked at EACH visit? What gets added after 20 weeks?
1) Vaginal bleeding
2) Vaginal discharge or leaking of fluid
3) Urinary symptoms
THEN
1) Contractions
2) Fetal movement
Components of the triple screen? Quad screen?
MSAFP (inc in NTD, dec in Down syndrome)
B-HCG
Estriol
Inhibin-A in quad screen
Second trimester visits?
- MSAFP between 15-18 wks
- Screening u/s between 18-20 wks
- Triple screen/quad screen
- Fetal heart is first heard
Third trimester visits? How often?
- Rhogam at 28 wks
- Leopold maneuvers 32-34 and beyond
- Breech are offered external cephalic version of fetus at 37-38 wks
- Vigorous exam of the cervix (“sweeping” the membranes) to determine probability of progressing post term or needing induction
- Vaginal cultures repeated in high risk ladies
- HSV latent: antiviral prophylaxis at 36 wks
- HSV active: plan c-section
- GBS screen beta 35-37 wks
Every 2-3 wks from 28-36 wks
Every week after 36 wks
WHEN IS “TERM”?
After 37 weeks
Lab tests during third trimester?
Hct (Hemoglobin below 11mg/dL start on iron supplements). Hct gets close to its nadir in 3rd trimester.
RPR/VDRL
GLT (glucose loading test)
PRETERM LABOR
LABOR THAT BEGINS BEFORE 37 WKS
Postterm pregnancy
After 42 weeks
GTT specifics
1) Fasting serum glucose measurement
2) 100g oral glucose loading dose
3) Measure serum glucose at 1, 2, 3 hours after oral dose
Thresholds for gestational diabetes diagnosis
Fasting gluc > 95
1 hour 180
2 hrs 155
3 hours 140
Routine u/s screening when?
18-20wks
BPP (biophysical profiles) look at what?
-Amniotic fluid volume
-Fetal tone
-Fetal activity
-Fetal breathing movements
-NST which tests FHR with fetal movement
Score of 2 each with a max of 10
8-10 is reassuring
Oxytocin challenge test (OCT) or contraction stress test (CST)
Why do you do them??
Get at least 3 contractions in 10 min
Concomitant FHR monitoring (reactivity criteria are the same as for NST)
If NST is nonreactive or FHR shows decelerations, or if BPP is non reassuring
NST is considered reactive if…
Two accelerations of FHR in 20 min that are at least 15 beats above baseline HR and last for at least 15 sec.
When would you do an NST in antenatal testing?
What if it’s nonreactive?
32-34 wks in high-risk pregnancies
40-41 wks in undelivered
Assess the fetus via ultrasound
What is PUBS used for?
percutaneous umbilical blood sampling
Fetal hematocrit level detection…
Like in Rh isoimmunization, fetal anemia, hydrops, fetal transfusion, fetal platelet count in alloimmune thrombocytopenia, karyotype analysis
Testing for fetal lung maturity?
Type II pneumocytes start secreting surfactant (they’ve used phospholipids to make it).
Lecithin/spingomyelin ratio increases with maturity.
Lecithin= lung maturity
Fetal lie
Longitudinal or transverse
Fetal presentation
Breech or vertex ( which can be cephalic if face first or not truly vertex)
Rupture of membranes suspected when?
Gush or leaking of fluid from vagina
This is sometimes hard to differentiate from stress incontinuence and small leaks of amniotic fluid
How do we diagnose ROM?
POOL, NITRAZINE (turns blue), FERN tests.
Vag is acidic, amniotic fluid is alkaline.
What can cause a false positive nitrazine test?
Fluid from cervix
What can you do if ROM tests are equivocal?
U/S to see fluid level. Oligohydramnios that was previously normal = ROM.
What if you REALLY need to know if it’s ROM (eg. PPROM when you need antibiotic prophylaxis)?
1) AMNISURE- rapid. Alpha-microglobulin-1 immunoassay.
2) Amniocentesis to inject dilute indigo carmine dye into the amniotic sac.
How do you obtain the Bishop score?
Cervical exam
What is in the Bishop score?
- Dilation
- Effacement
- Fetal station
- Cervical position
- Consistency of the cervix
With what Bishop score is a cervix favorable for spontaneous and induced labor?
8 or higher
What is station? Where is +3?
Relation of the FETAL HEAD to the ISCHIAL SPINES.
+3 is at the introitus