normal flora of GI

Question 1

What are normal flora?

Answer 1

symbiotes because they live in close association with the host.

Question 2

commensal

Answer 2

organism benefits but the host does not

Question 3

What type of bacteria predominates in the GI tract

Answer 3

greater than 90% are anaerobic gram negative bacteria

Question 4

What are most gram negative bacteria

Answer 4

bacilli, 10 7 are facultative

Question 5

What are the beneficial effects o the normal flora

Answer 5

prime the immune system, induce isohemagglutins by cross reactions, exclude pathogens

Question 6

Humans can be sensitized to what bacteria

Answer 6

clostridium difficile

Question 7

What anaerobes are most numerous

Answer 7

bacteroides

Question 8

Facultative gram negative bacteria

Answer 8

eschericia coli, klebsiella, enterobacter, proteus , pseudomonos aeruginosa , serratia, citrobacter

Question 9

gram positive cocci

Answer 9

enterococcus , staph aureus

Question 10

What pathogenic effects can normal flora have?

Answer 10

malabsorption syndromes, cancer by production of nitrosamines, UTI, pneumonia, other diseases can escape GI tract, escape of gram negative can lead to sepsis, bacteremia, endotoxic shock

Question 11

What is sepsis

Answer 11

Dysregulated host response to infection, occurs when gram negative bacteria is present in blood. Causes fever, hypotension, leukocytosis, multiple organ dysfunction

Question 12

What are primary causes of sepsis

Answer 12

focal infection that spreads to blood stream. Meningococcal meningitis, UTI, pseudomonoas burns, pneumonia, Breach of GI tract by injury, appendicitis, latrogenic