Norepinephrine (Levophed)

Question 1

Norepinephrine (Levophed) indications

Answer 1

Hypotension in the absence of hypovolemia

Question 2

Norepinephrine (Levophed) contraindications

Answer 2

Hypovolemia
Vascular thrombosis
Renal failure (relevant)

Question 3

Norepinephrine (Levophed) dose for post cardiac arrest hypotension (fluid resistant)

Answer 3

0.1 - 0.5 mcg/ kg/ min IV/ IO infusion titration to effect (usual 7-35 mcg/ kg/ min)

Question 4

Norepinephrine (Levophed) dose for septic shock

Answer 4

0.1 - 0.5 mcg/ kg/ min IV/ IO infusion, titration to effect. Doses up to 3 mcg/ kg/ min may be necessary to correct hypotension.

Question 5

Norepinephrine (Levophed) pediatric dose for hypotension/ shock

Answer 5

0.05 - 0.1 mcg/ kg/ min infusion titration to effect. (Usual max dose 2 mcg/ kg/ min)

Question 6

Norepinephrine (Levophed) kinetics

Answer 6

Onset: seconds
Duration: 1-2 mins