Non-Prescription Treatment Options Flashcards
1
Q
Why Non-Prescription Options?
A
- Vets and owners are actively seeking prescription-free solutions to help minimize inappropriate behavior, phobia, fear, and anxiety seen in out pets
- Fear Free movement is creating an increased demand for prescription-free supplements
- Supplements can aid in training and behavior modification therapy by facilitating a calm and receptive attitude
2
Q
Non-Prescription Options
A
- Neutraceuticals
- Therapeutic Diets
- external Devices/Garments
- Pheromones
- Essential oils/Aromatherapy
- Music
- Desensitization via recordings
- Massage, Acupressure and Acupuncture
- Environmental manipulation and enrichment
3
Q
Neutraceuticals
A
- Natral, bioactive chemical compounds that have health-promoting, diesease preventing or general medicinl properties
- Vitamins
- Amino Acids
- Minerals
- Herbal or other botanical supplements
- Certain animal products
- Includes Functional foods
- foods that tout a specific health benefit based on their ingredients
4
Q
Neutraceuticals in the US
A
- The term “nutraceutical” products are regulated as:
- Drugs
- Food ingredients
- Dietary supplements
- Not defined the same in different countries
- usually defined as a product isolated from foods that is sold in medicinal forms, but not associted with food
5
Q
Neutraceutical Regulation
A
- No patent protection
- Can be used to cure or prevent disease
- ONLY pharmaceutical compounds have government sanction
- FDA regulates
- Nutraceutical are under a different set of regulations compared to food or drug products
- Dietary Supplement Health and Education Act (DSHEA) 1994:
- It is the manufacturer’s responsibility to ensure safety of nutraceutical before its marketed
-
Current Good Manufacturing Practice (CGMP) regulation Goals:
- Safety and labeling
- less emphasis on product clsims and intended use
6
Q
FDA
A
- Authorized to take action against any unsafe product after it reaches market
7
Q
Manufacturers Responsibility
A
- Have to make sure that the information on the product label is truthful and not misleading
- NOT obligated to register their poductswith the FDA NOR get FDA approval before producing or selling nutraceuticals
8
Q
Quotes From Fear Free
A
- In the mind of the consumer they are different because they are ‘natura’ and that is something that a lot of people are looking for
- “Natural” doesn’t necessarily equal “safe”, the naural world is chock-full of poisonous substances. In some cases, clients may simply need some reassurance about the drug options
- When they think of a supplement, they don’t think it’s goint to affect their animals as strongly as they perceive a behavioral drug does
- What I tell my clients and veterinarians is, we try to use supplements from companies we trust - as much as you can trust a company….We try to use supplements made by pharmaceutical companies. Its not that I love pharmaceutical compnies, but I can hold someone responsible
- Whatever your source, read the research and evaluate the evidence yourself. Given the lack of regulation, you first need to know if a product has been properly tested for safety in dogs and cats..
9
Q
Evaluating Nutraceuticals
according to Fear Free
A
-
Species used in the study
- was the research on dogs/cats or rats/mice
-
Condition studied
- If a study was narrowly focused on some aspect, for example separation anxiety, it may not work on other types of anxiety
-
What was evaluated
- Acutal behavior or physical measurements such as stress hormones
- both types have Pros and Cons
- Acutal behavior or physical measurements such as stress hormones
10
Q
Nutraceuticals for Behavior Modification
A
- Rescue Remedy
- Harmonease
- Anxiety TFLN
- Anxitane
- Solliquin
- Composure and Composure Pro
- Hemp/CBD products
- Melatonin
11
Q
Rescue Remedy Pets
A
- A blend of 5of the 38 Bach Original Flower Remedies
- Add 4 drops of rescue remedy to your pet’s food, water bowl, or on a treat. Repeat as needed. Can also be rubbed on the ears, nose, or paw
- Dosage of Rescue Remedy Pet dose not depend on weight or type of animal. It depends on the situation of stress. It is not a sedative, so find the dosage that works best for you and your pet
12
Q
Harmonease (VPL)
A
- Harmonease is a natrual proprietary blend of a patented extract of Magnolia officinalis and a proprietary extract of Phellodendron amurense
-
Phellodendron amurense demonstrated significant anti-stress effects in rodent tests
- UNSAFE for pregnanc in people
- Magnolia officinalis contians a mixture of honokiol and magnolol both of which have been identified as modulators of the GABAA receptors for activity to decrease stress
- Dogs:
- Up to 50 lbs: 1/2 tablet 1x day
- Over 50 lbs: 1 tablet 1x day
13
Q
Anxxiety TFLN
Thunder, Fireworks, and Loud Noises
A
- Ingredients:
- Borate of Sodium - Washing soda
- Rhododendron chrysanthum
- Phosphorus
- German Chamomile
- Theridion curassavicum (Orange spider)
- In acute cases, can give every 15 minutes, up to 4 doses
- In chronic/long-term problems: 1 dose 3x daily
- ofen started 5-7 days before anxiety causing situation
- Once response seen reduce to 2x daily
-
If remedy is working well and dosing is not reduced, and aggravation of symptoms from overuse may occur
- Stopping for 3 days will reverse symptoms, then treatment can befin again as if using for the first time, weaning down as mentioned abobe
14
Q
Anxitane
A
- Contains pre L-Theanine, aka Suntheanine, an amino acid that acts neurologically to help keep dogs and cats calm, relaxed, and well-behaved
- Fo optimal results, prescribe for at least 30 days for pets experiencing behavior changes in response to stress
- Flavored chewable tablets are palatable fro dogsand cats and allow for easy administration and better compliance
- All-natural nutritional supplement that is not-habit-forming
- WARNING: Not intended for use in animals with severe phobias, separation anxiety or in animals with a known history of agression
15
Q
Zylkene
A
- Bovine-sourced hydrolyzed milk protein
- has calming properties
- lactose-free
- Helps balance reaction sin some situations
- Travel, moving, adoption, grooming, meeting new people, loud noises, etc
- Helps animals maintain normal and relaxed dispositions
- May also open pets’ receptivity to behavior modification training
- Capsules can be administered orally, or opened and added to a meal
- Can be used daily or as needed
- Shor-term: use 1-2 days before event/change
16
Q
Composure
A
- A calming supplement to support relaxation in situations that cause nervousness, anxiety, or stress
- Active Ingredients per Chew:
-
Thiamine (Vit B1): 134mg
- affects CNS to help calm
-
Colostrum Calming Complex Biopeptide Blend 22mg
- supports stress reduction and cognitive function
-
L-Theanine 21mg
- helps body produce other AA to being neurotransmitters back to balance
-
Thiamine (Vit B1): 134mg
- Ingredients work synergistically to support relaxation without chaning your dog’s personality or energy levels
17
Q
Composure Dosing
A
- Dose:
- Up to 50 lbs: 1 chew daily
- 51-100 lbs: 2 chews daily
- over 100 lbs: 3 chews daily
- Can be given daily or on an as needed basis
- Safe to double or triple the dose in times of increased stress
- CAUTION: Safety in pregnant animals or animals intended for breeding has NOT been proven
18
Q
Composure Pro
A
- Per chew
- Thiamine (Vit B1) 100 mg (134mg in original)
- L-Tryptophan 75 mg (0 mg in original)
- Col. Calm. Complex Biopeptide Blend 25 mg (22 mg in original)
- L-Theanine 25 mg (21 in original)
19
Q
L-Tryptophan
A
- An essential AA that helps the body make proteins and certain brain-signaling chemicals
-
The body changes L-tryptophan into serotonin
- serotonin helps control mood and sleep
- Has potential to cause serotonin syndrome when given with other serotonin level altering drugs
20
Q
Solliquin
Nutramax
A
-
L-theanine:
- An AA found naturally in green tea.
- Directly stimulates the production of alpha brain waves, creating a state of deep relaxation, wakefulness, and mental awareness
-
Magnolia/Phellodendron:
- Combination appears to be synergistic
- Controls stress and anxiety more effectvely than either compound alone
-
Whey Protein Concentrate:
- Contains NMXSLQ05, a trademarked high quality protein source which supplements 10 AAs including precursors of glutathione and serotonin
21
Q
Hemp Products (CBD oil)
A
- TNTC
- No Regulation on strength and potency
- CBD (Cannabidiol) does not contain THC
- Still illegal to use in some states
- May 24, 2018 it is not unlawful under state law to possess or sell products or substances containing any amount of Cannabidiol
- Some state only allow CBD that comes from industrial hemp
- Usually not just hemp in calming products
22
Q
Melatonin
A
- A hormone supplement
- can be given alone or in combinaitno
- Used to treat:
- Sleep disorders
- Behavioral disorders
- Adjunct therapy as pre-visit medication for aggressive dogs
- Side effects are uncommon:
-
Changes in fertility
- Can decreasecortisol and estradiol levels
- Sleepiness
- Weight gain
-
Changes in fertility