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Pharm Test 4 > Non-Opoids > Flashcards

Non-Opoids Flashcards

1
Q

What is the trade name for acetylsalicylic acid (ASA)

What type of drug is it

A

Aspirin

NSAID (different chm than normal)

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2
Q

What is the mechanism of acetylsalicylic acid

A

Cox 1/2 inhib

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3
Q

When is the indications of aspirin

A

MI (emergency kit)

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4
Q

What are the contraindications of aspirin

A

Viral pts esp in kids, gout, GERD, hernia, asthma, anticoagulants, chronic gastritis, third trimester (prolonged labor, hemmorhage, premature duct closing.) Methotrexate

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5
Q

What should you prescribe instead of Methotrexate with aspirin

A

acetomin

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6
Q

What are the side effects of Salicylism-

A

confusion, tinnitus, dizziness, nassau, vomiting

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7
Q

What are the possible cross reactions with aspirin

A

other NSAIDS Blocks clearance of methotrexate (for autoimmune and chemotherapy

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8
Q

What other adverse effects come from asprin

A

Salicylism- confusion tinnitus, dizziness, naseau, vomitting

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9
Q

A patient with cardiac stents should be taken off of what but not Asprin

A

Plavix

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10
Q

True or false, Older patients need to come off of aspirin for dental work

A

False

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11
Q

What is the mechanism for general NSAIDS

A

COX inhibitor

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12
Q

What are the indications for a need of NSAIDS

A

pain fever inflammation

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13
Q

What are the contraindications for NSAIDS

A

advanced renal disease, with ibuprofen, kidney or liver issues

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14
Q

What are the side effects of NSAIDS

A

CNS, skin reactions (cross-sens with aspirin)

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15
Q

What cross reactions can occur when taking taken with alcohol and smoking

A

Bleeding

Blocks exertion of lithium

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16
Q

True or false, NSAIDS cause MI/stroke, hypotension, nephropathy, and Steven-Johnson syndrome

A

FALSE HYPERTENSION

17
Q

What is the mechanism for ibuprofen

A

It blocks cox 1 and 2

18
Q

What is a contraindication for ibuprofen

A

Methatrexate script acetomin instead

19
Q

Methotrexate when taken with ibuprofen can cause what type of cross reaction

A

Interfere with the platelet effect of ibuprofen

20
Q

Naproxen or Aleve Anaprox or Naprosyn uses what type of mechanism and is what type of drug

A

Cox 1 and 2 blocker and NSAID

21
Q

Aleve is though to not work very well, what is important while taking aleve

A

It works much better if you don’t neglect the loading dose

22
Q

What is the max dose for ibeprophen

A

`1200 mg (gi and kidney complications above that amount.

23
Q

What is the optimal analgesia

A

400mg higher is for the antiinflamatory

24
Q

What is an example of a selective NSAID

A

celecoxib or Celebrex, its a special NSAID

25
Q

What is the mechanism for celcoxib or Celebrex

A

Blocks Cox 2

26
Q

What is a drug that works well specifically on arthritis pain and is approved for dentistry

A

Celecoxib Celebrex, great for analgesia

27
Q

True or false,Pregnancy is a contraindications for Celecoxib or Celebrex

A

True

28
Q

What is a side effect of Celezoxib

A

still have bleeding issues should be different mechanism than cox 1 and 2 inhibs

29
Q

What other adverse effects come with taking Celexoxib or celebrex

A

Strokes and heart attacks all other COX 2 inhibits were pulled for this reason

30
Q

Celebrex chronic use can delay what

A

Alzheimers , also benefits for cancer

31
Q

Acetaminophen/Tylenol is characterized as what type of drug

A

Misc analgesic

32
Q

What is the mechanism for acetaminophen

A

Blocks COX 3, used for analgesia, antipyresis NOT antinflamamation

33
Q

True or false acetaminophen is a great anti-inflammatory drug

A

FALSE IT IS NOT

34
Q

What problems can occur from taking acetaminophen

A

Liver disease/dysfunction HX of alcoholism

35
Q

What should not be taken with acetaminophen and what can happen

A

Coumadin, can increase bleeding time 10x, also increased risk for NSAIDS but acetomin better for short term analgesia

36
Q

True or false acetaminophen causes brochoconstriction

A

False

37
Q

True or false acetaminophen can platelet inhibition, irritate GI

A

False NSAIDS and aspirin cause these thing

38
Q

Tylenol dropped their upper limit because of what

A

High presence of liver disease in the US

Pharm Test 4 (2 decks)

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