Non-opiod analgesics Flashcards
NSAID action?
- Inhibition of COX-1 can result in decreased platelet aggregation and kidney damage
- inhibition of COX-2 results in decreased inflammation, fever, and pain and does not decrease platelet aggregation
NSAID uses?
- Inflammation suppression
- analgesia for mild to moderate pain
-Fever reduction - Dysmenorrhea
- Inhibition of platelet aggregation
Second Gen NSAIDS?
- Celecoxib
NSAIDS complications?
- Dyspepsia
- Abdominal pain
- heartburn
- Nausea
NSAID pt education?
- Take medication with food or with a 8oz glass of water or milk
- avoid alcohol
Impaired kidney function s/sx?
- Decreased urine output
- weight gain
- increased BUN
- creatinine levels
nursing actions for kidney impairment?
- Use cautiously with older adults and pt with heart failure
- Monitor I/O and kidney function ( BUN and creatinine)
NON Aspirin NSAID’s
-increased risks of heart attack and stroke
Non Aspirin NSAIDS nursing actions?
-Use the smallest effective dose for pt who have cardiovascular disease
What occurs with aspirin?
-Salicylism
Manifestations of salicylism
-Tinnitus, sweating, headache, dizziness, and respiratory alkalosis
Education for Salicylism?
-notify the provider and stop taking aspirin if the manifestations occur
what is Reye’s syndrome?
- this occurs when aspirin is used for fever reduction in children and adolescents who have viral illness (chickenpox, influenza)
Aspirin toxicity actions?
- manage as a medical emergency
- activated charcoal can be given decreased absorption
- hemodialysis can be indicated
- cool the client with tepid water
-correct dehydration and electrolyte imbalance with the IV fluids
NSAID contraindications?
-Pregnancy
-peptic ulcer disease
-bleeding disorders
- Hypersensitivity to aspirin and other NSAIDS
- contraindicated in children with influenza or chicken pox
NSAID cautions?
- use caution with older adults
- pt’s who smoke
- pt’s taking ACE inhibitors, and ARBS
Ketorolac contraindications?
- contraindicated in pt’s who have advanced kidney disease
-do not use longer than 5 days because of the risk for GI, renal, and cardiovascualar complications
Second Gen NSAIDS use?
- Celecoxib as NSAID COX-2 inhibitors are a last choice medication for chronic pain due to increased myocardia infarction, stroke, and suppression vasodilation
Second Gen NSAIDS anticoagulants
- anticoagulants increase the risk of bleeding
Anticoagulants actions?
- Monitor PTT, PT, and INR
Anticoagulant pt education?
- remain aware of the potential risk of bleeding when an NSAID is combined with an anticoagulant
- report indications of bleeding
