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PHRM844 > Non-Insulin Therapy > Flashcards

Non-Insulin Therapy Flashcards

1
Q

metformin brand names

A

-Glucophage
-Fortamet
-Glumetza

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2
Q

SGLT2 inhibitors

A

-canagliflozin
-dapagliflozin
-empagliflozin

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3
Q

canagliflozin brand name

A

Invokana

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4
Q

dapagliflozin brand name

A

Farxiga

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5
Q

empagliflozin brand name

A

Jardiance

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6
Q

canagliflozin dose for eGFR > 60

A

-100 mg PO QD
-max: 300 mg PO QD

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7
Q

canagliflozin dose for eGFR 30-60

A

-max: 100 mg PO QD if no albuminuria

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8
Q

canagliflozin dose for eGFR < 30

A

-do not start canagliflozin
-if already taking, may take 100 mg PO QD if albuminuria > 300 mg/day

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9
Q

dapagliflozin dose for eGFR > 45

A

-5 mg PO QD
-max: 10 mg PO QD

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10
Q

dapagliflozin dose for eGFR < 25

A

-do not start dapagliflozin
-if already taking, may continue and monitor

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11
Q

empagliflozin dose for eGFR > 30

A

-10 mg PO QD
-max: 25 mg PO QD

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12
Q

empagliflozin dose for eGFR < 30

A

-do not start empagliflozin
-if already taking, may continue and monitor

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13
Q

ertugliflozin dose for eGFR > 60

A

-5 mg PO QD
-max: 15 mg PO QD

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14
Q

ertugliflozin dose for eGFR < 45

A

-do not start ertugliflozin
-if already taking and eGFR is low, then discontinue

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15
Q

GLP-1 agonists

A

-liraglutide
-dulaglutide
-semaglutide

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16
Q

liraglutide brand name

A

Victoza

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17
Q

dulaglutide brand name

A

Trulicity

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18
Q

semaglutide brand names

A

-Ozempic
-Rybelsus

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19
Q

dulaglutide dosing

A

-0.75 mg SQ QW up to 4.5 mg SQ QW
-use with caution in pts with ESRD

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20
Q

dulaglutide needles?

A

attached to pens

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21
Q

semaglutide dosing

A

-0.25 mg SQ QW for 4 weeks, then 0.5 mg SQ QW up to 2 mg SQ QW

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22
Q

semaglutide needles?

A

in pen carton

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23
Q

liraglutide dosing

A

-0.6 mg SQ QD for 7 days, then 1.2 mg SQ QD up to 1.8 mg SQ QD

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24
Q

liraglutide needles?

A

not included

25
Byetta dosing
-5 mcg SQ BID for 1 month, then 10 mcg SQ BID -avoid in pts with CrCl < 30 mL/min
26
Byetta needles?
not included
27
Bydureon Bcise dosing
-2 mg SQ QW -avoid in pts with CrCl < 30 mL/min
28
Bydureon Bcise needles?
included
29
lixisenatide dosing
-10 mcg SQ QD for 14 days, then 20 mcg SQ QD -avoid in pts with eGFR < 15
30
lixisenatide needles?
not included
31
dual GLP-1 agonist and GIP
tirzepatide
32
tirzepatide brand name
Mounjaro
33
DPP-4 inhibitors
-sitagliptin -saxagliptin -linagliptin -alogliptin
34
sitagliptin brand name
Januvia
35
saxagliptin brand name
Onglyza
36
linagliptin brand name
Tradjenta
37
alogliptin brand name
Nesina
38
sitagliptin dose for CrCl > 50 mL/min
100 mg PO QD
39
sitagliptin dose for CrCl 30-50 mL/min
50 mg PO QD
40
sitagliptin dose for CrCl < 30 mL/min or patients with ESRD on HD
25 mg PO QD
41
saxagliptin dose for CrCl > 50 mL/min
2.5 mg - 5 mg PO QD
42
saxagliptin dose for CrCl < 50 mL/min
2.5 mg PO QD
43
linagliptin dose
5 mg PO QD (not excreted by kidneys, so no dosage adjustment required)
44
alogliptin dose for CrCl > 60 mL/min
25 mg PO QD
45
alogliptin dose for CrCl 30-60 mL/min
12.5 mg PO QD
46
alogliptin dose for CrCl < 30 mL/min or patients with ESRD on HD
6.25 mg PO QD
47
sulfonylureas
-glyburide -glipizide
48
glyburide brand names
-Diabeta -Micronase -Glynase
49
glipizide brand names
-Glucotrol -Glucotrol XL
50
Glucotrol starting dose
2.5 mg - 5 mg PO QD
51
Glucotrol max dose
40 mg (but stop at 20 mg if not seeing much BG benefit)
52
Glucotrol XL starting dose
2.5 mg - 5 mg PO QD
53
Glucotrol XL max dose
20 mg PO QD
54
Micronase/Diabeta starting dose
1.25 mg - 5 mg PO QD
55
Micronase/Diabeta max dose
20 mg PO QD
56
Glynase starting dose
1.5 mg - 3 mg PO QD
57
Glynase max dose
12 mg PO QD
58
thiazolidinedione
pioglitazone
59
pioglitazone brand name
Actos

PHRM844 (4 decks)

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