Non experimental designs Flashcards

1
Q

name the 3 types of non experimental design

A

1) Descriptive correlational study
2) Case-control study
3) Cohort study

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2
Q

what is cohort study?

A

It refers to ‘‘any
designated group of individuals who share
a common experience or condition”

It defines two or more groups of people that are free
of disease at the beginning but differ on their
exposure (e.g. smoking status) to a potential
causes of the diseases.

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3
Q

what does cohort study investigate?

A

it investigates the etiology of disease based on one’s exposure to toxic/ carcinogenic substances.

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4
Q

define exposed cohort

A

individuals experienced the
putative causal event or condition (i.e. smokers)

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5
Q

define reference cohort

A

Reference cohort – individuals thought of
unexposed to the condition (i.e. non-smokers)

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6
Q

what is the most straightforward type of epidemiologic study?

A

cohort study

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7
Q

what is the primary goal of cohort study?

A

to measure and usually to
compare the incidence of disease or
event in the study cohorts.

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8
Q

Name the 4 types of cohort studies:

A

1)prospective cohort
2)retrospective cohort
3)ambi-directional cohort
4) nested case control

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9
Q

what is prospective cohort?

A

it is looking forward, likely to happen in the future.

defines a sample and predictor
variables before any outcomes (diseases)
have occurred and then collect the data for
the study in a prospective manner

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10
Q

name 4 strengths of prospective study:

A

1) Able to control how to measure the exposure
2) Able to measure confounding variables
3) Avoid recall bias
4) Able to calculate relative risk for the outcome

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11
Q

what are 2 weaknesses of cohort study?

A

1) costly
2) lengthy

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12
Q

what is retrospective cohort?

A

it takes effect from the past.

defines a sample and predictor variables after
outcomes (diseases) have occurred. The
data basically exists and the investigators
use the data to answer the questions in
interest.

examples:
A retrospective cohort study on the risk of obesity among
shift workers

A retrospective cohort study of the Nagasaki atomic bomb
survivors for the risk of preleukemia.

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13
Q

what are the 3 strengths of retrospective cohort study?

A

1) Inexpensive
2) Time-saving
3) Able to study longitudinally with long latent periods

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14
Q

what are the 4 weaknesses of retrospective studies?

A

1) Risk of confounding variables - cannot measure as data has been collected

2) Sometimes unable to determine exact exposure
- unable to use an exact scale

3) Measurement error
4) Selection bias
- unable to control how participants of primary data were selected for inclusion

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15
Q

what is ambi directional cohort?

A

combination of retrospective and prospective to gain more information to help answer the question.

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16
Q

1 Strength for Ambi-directional cohort study

A

Captures exposures that can cause both short-term &
long-term outcomes

17
Q

3 Weaknesses of ambi-directional cohort study

A

1) Costly and lengthy
2) Risk of confounding variables
3) Exposure determination problems

18
Q

define risk for cohort study analysis

A

Risk is defined as the probability that an event occur and
it is measured as incidence rate (IR) in cohort study

19
Q

What is rate ratio/ risk ratio/ relative risk.

A

Define as the
ratio between the incidence rates of the two groups,
can be used to compare the risk in the two groups:
RR=IR E /IRNE

20
Q

what is the purpose of descriptive study?

A

To observe, describe and document aspects of a
situation

21
Q

what is the purpose of descriptive correlational study

A

To examine a relation between variables without
attempting to infer causal relationship

22
Q

what are the 5 methods of analysis for simple descriptive study?

A

Descriptive statistics like
mean,
standard deviation,
median,
frequency,
percentage, etc.

23
Q

what are the 4 methods of analysis for descriptive correlational study?

A

Descriptive correlational study –
Pearson’s
correlation,
Spearman’s rank correlation,
regression,
logistic regression, etc.