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Therapeutics > Non-Dihydropyridine Calcium Channel Blockers > Flashcards

Non-Dihydropyridine Calcium Channel Blockers Flashcards

1
Q

Non-Dihydropyridine Calcium Channel blockers MOA

A

inhibits calcium ions from entering vascular smooth muscle and myocardium (selective to myocardium)
negative inotropy and chronotropy

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2
Q

Non-Dihydropyridine Calcium Channel blockers Contraindications

A

Hypotension, Cariogenic Shock, HFrEF

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3
Q

Non-Dihydropyridine Calcium Channel blockers interactions

A

CYP3A4 substrate and inhibitor. Simvastatin and Lovastatin need dose adjustments, routine beta-blockers

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4
Q

Non-Dihydropyridine Calcium Channel blockers Adverse Effects

A

Edema, headache, bradycardia, conduction disturbances, Heart Failure exacerbation, constipation

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5
Q

Verapamil adverse effects

A

constipation, gingival hyperplasia

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6
Q

Diltiazem ER

A

Cardizem

120-360mg QD

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7
Q

Verapamil

A

Canalan

120-360mg QD

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Therapeutics (6 decks)

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