Non-

Question 1

Entamoeba coli

Answer 1

Non-pathogenic amoeba, larger than E. histolytica, found in the colon, with sluggish non-directional motility.

Question 2

E. coli vs. E. histolytica

Answer 2

E. coli has blunt pseudopodia, sluggish movement, eccentric karyosome, no RBC ingestion, and 8 nuclei in mature cysts.

Question 3

Entamoeba gingivalis

Answer 3

Found in the mouth, common in gum disease (pyorrhea), no cyst stage, transmitted via kissing, droplets, or utensils.

Question 4

Naegleria fowleri

Answer 4

Free-living pathogenic amoeba causing primary amebic meningoencephalitis (PAM). Enters through the nasal cavity into the brain.

Question 5

Acanthamoeba spp.

Answer 5

Causes granulomatous amebic encephalitis (GAM) and keratitis. Enters through mucosa, eyes, or wounds.

Question 6

Naegleria vs. Acanthamoeba

Answer 6

Naegleria has 3 stages (amoeboid, flagellated, cyst), only trophozoites in the brain, while Acanthamoeba has 2 stages (amoeboid, cyst), both found in the brain.

Question 7

Diagnosis of Naegleria

Answer 7

CSF examination.

Question 8

Diagnosis of Acanthamoeba

Answer 8

Brain biopsy or corneal scrape; CSF examination may be negative.

Question 9

Treatment of Naegleria

Answer 9

Amphotericin B (not very effective).

Question 10

Treatment of Acanthamoeba

Answer 10

Miconazole (not very effective), keratoplasty in severe cases.

Question 11

Habitat of Naegleria

Answer 11

Primarily the brain.

Question 12

Habitat of Acanthamoeba

Answer 12

CNS, eye, and other tissues.