Nociception Flashcards

1
Q

What are the two pathways that carry sensory information to the primary sensory cortex?

A

Medial lemniscus

Spinothalamic

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2
Q

What type of sensory information does the medial lemniscal pathway carry?

A

Touch, proprioception

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3
Q

What type of sensory information does the spinothalamic pathway carry?

A

Pain, temperature

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4
Q

Which receptors contribute to the medial lemniscus pathway?

A

Proprioceptors, mechanoreceptors

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5
Q

Which receptors contribute to the spinothalamic pathway?

A

Nociceptors, thermoreceptors

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6
Q

Where does the primary somatosensory cortex receive inputs from?

A

Ventral posterior thalamic nuclei

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7
Q

Neurons in S1 of the primary sensory cortex are very responsive to what type of stimuli?

A

Somatosensory

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8
Q

What do lesions in S1 result in?

A

Impaired somatic sensations

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9
Q

What is a homunculus?

A

A depiction of the human body created from a cortical map that represents distinct body areas and their relative importance of sensory information and motor control

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10
Q

What are the five sensory modalities?

A

Vision, hearing, smell, taste, touch

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11
Q

What are examples of somatic sensation?

A

Touch, nociception, proprioception, temperature

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12
Q

What is pain?

A

Unpleasant sensory or emotional experience that is associated with either actual or potential tissue damage. It is subjective

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13
Q

What is nociception?

A

Processing of information about damaging stimuli

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14
Q

How do nociceptors innervate tissue?

A

Have free nerve endings in every tissue of body except for brain

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15
Q

What type of stimuli activates nociceptors?

A

Intense thermal, mechanical, chemical stimuli

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16
Q

How does tissue irritation/injury activate nociceptors?

A

Induces release of chemicals (such as potassium, prostaglandins etc) that stimulate nociceptors