NMBD Dosing With Reversals

Question 1

Succinylcholine Dosing

Answer 1

ED 95 0.3 mg/kg
Intubating 1 mg/kg
Onset 30-60 sec
Duration 10 min
Pseudocholinesterase

Question 2

Vecuronium dosing

Answer 2

ED 95 0.05 mg/kg
Intubating 0.1 mg/kg
Onset 3-4 min
Duration 25-50 min
10-50% renal

Question 3

Rocuronium Dosing

Answer 3

ED95 0.3 mg/kg
Intubating 0.6-1.2 mg/kg
Onset 1.5-3 min
Duration 30-70 min
30% Renal

Question 4

Pancuronium Dosing

Answer 4

ED 95 0.07 mg/kg
Intubating 0.1 mg/kg
2-4 min onset
60-120 min duration
40-70% renal
Vagal Block=tachycardia

Question 5

Mivacurium dosing

Answer 5

ED95 0.08 mg/kg
intubate 0.2 mg/kg
3-4 min onset
Duration 15-20 min
Plasma cholinesterase
HISTAMINE

Question 6

Atracurium dosing

Answer 6

ED 95 0.25 mg/kg
Intubate 0.5 mg/kg
Onset 3-5 min
Duration 30-40 min
HISTAMINE

Question 7

Cisatracurium dosing

Answer 7

ED95 0.05 mg/kg
Intubating 0.2 mg/kg
Onset 4-7 min
Duration 35-50 min
Hoffman/ester elimination

BEST in renal impairment

Question 8

Doxacurium

Answer 8

Ultra long
80-120
Variable onset time

Question 9

ADP TOF 0 twitches

Answer 9

16 mg/kg Sugammadex

WAIT?!?

Question 10

ADP TOF 1-2 twitches

Answer 10

4mg/kg Sugammadex

Question 11

Receptor occupancy
1.0

Answer 11

25-50%

Question 12

Receptor occupancy
0.75-0.9

Answer 12

70-75%

Question 13

Receptor occupancy with
TOF 0.6-0.75

Answer 13

80-85%