NMBD doses Flashcards
Succ intubation dose
1 mg/kg
Succ RSI dose
1.5 mg/kg
Succ onset
30-90 seconds
Succ Duration
9-13 minutes
Succ metabolism
Pseudocholinesterase
succinylmonocholine is metabolite
Roc intubating dose
0.6- 1 mg/kg
Rocc RSI dose
1.2 mg/kg
Rocc ED95
0.3 mg/kg
Roc onset
45-90 seconds
Roc maintenance dose
0.1 mg/kg
Roc duration
30-60 min
Roc metabolism
70% hepatic
30% renal
Biliary excretion
No metabolites
Vec intubation dose
0.1-0.2 mg/kg
Vec onset
2-4 minutes
Vec maintenance dose
0.02 mg/kg
Vec metabolism
Hepatic
3-OH - active metabolite
Panc intubation dose
0.1 - 0.15 mg/kg
Panc Onset
2-4 minutes
Panc Maintenance dose
.02 mg/kg
Best drug for renal and liver failure patients
Cis
Atracurium is also but produces histamine
Succ ED95
0.3 mg/kg
Vec duration
30-45 minutes
Panc ED95
0.075 mg/kg
Vec ED95
0.05 mg/kg
Panc duration
45-90 min
Cis intubating dose
0.1 - 0.2 mg/kg
Cis ED95
0.05 mg/kg
Cis onset
2-4 minutes
Cis Maintenence dose
0.02 mg/kg
Cis duration
45-60 min
Cis metabolism
Hofmann
Laudanosine
Atracurium intubating dose
0.5-0.6 mg/kg
Atracurium ED95
0.15 mg/kg
Atracurium onset
2-3 minutes
Atracurium maintenance dose
0.1 mg/kg
Atracurium duration
30-60 minutes
Atracurium metabolism
Hofmann
Laudanosine
Mivacurium intubating dose
0.15-0.25 mg/kg
Mivacurium ED95
0.08 mg/kg
Mivacurium onset
2-3 minutes
Mivacurium maintenance dose
0.1mg/kg
Mivacurium duration
15-20 minutes
Mivacurium metabolism
pseudocholinesterase
Neostigmine dose for 2 twitches
0.07 mg/kg
Neostigmine dose for 3-4 twitches
0.04 mg/kg
Neostigmine dose range and max dose
0.02-0.07 mg/kg
max 5mg
Neostigmine onset
5-15 minutes
Neostigmine duration
45-90 minutes
Neostigmine metabolism
50% renal 50% hepatic
Edrophonium dose
0.5-1 mg/kg
Need 4 twitches back to give!
Edrophonium onset
1-2 minutes
Edrophonium duration
30-60 minutes
Edrophonium metabolism
75% renal
25% hepatic
Pyridostigmine dose
0.1-0.3 mg/kg
Pyridostigmine onset
10-20 minutes
Pyridostigmine duration
60-120 minutes
Pyridostigmine metabolism
75% renal
25% hepatic
Suggamadex dose for 2 TOF twitches
2 mg/kg
Suggamadex dose for PTC 1-2
4mg/kg
Suggamadex dose for profound block/3-5 minuntes after NMBDs
16 mg/kg
Dose of roc if it’s been 5 minutes since 4mg/kg of suggamadex
1.2 mg/kg
NMB drug and dose if it’s been 4 hours since reversal with suggamadex
0.6mg/kg Roc
or
0.1mg/kg vec
Dosing for glyco
0.01-0.02 mg/kg
0.2 mg per 1 mg of neostigmine
Onset of glyco
2 min
Duration of glyco
2-4 hours
Dose of atropine with edrophonium
7 mcg/kg
Dose of atropine with neostigmine
0.015 mg/kg
Onset atropine
1-2 min
Duration atropine
1-2 hours
