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pharmacodynamics anesthesia > NMBD doses > Flashcards

NMBD doses Flashcards

1
Q

Succ intubation dose

A

1 mg/kg

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2
Q

Succ RSI dose

A

1.5 mg/kg

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3
Q

Succ onset

A

30-90 seconds

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4
Q

Succ Duration

A

9-13 minutes

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5
Q

Succ metabolism

A

Pseudocholinesterase
succinylmonocholine is metabolite

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6
Q

Roc intubating dose

A

0.6- 1 mg/kg

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7
Q

Rocc RSI dose

A

1.2 mg/kg

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8
Q

Rocc ED95

A

0.3 mg/kg

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9
Q

Roc onset

A

45-90 seconds

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10
Q

Roc maintenance dose

A

0.1 mg/kg

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11
Q

Roc duration

A

30-60 min

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12
Q

Roc metabolism

A

70% hepatic
30% renal
Biliary excretion
No metabolites

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13
Q

Vec intubation dose

A

0.1-0.2 mg/kg

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14
Q

Vec onset

A

2-4 minutes

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15
Q

Vec maintenance dose

A

0.02 mg/kg

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16
Q

Vec metabolism

A

Hepatic
3-OH - active metabolite

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17
Q

Panc intubation dose

A

0.1 - 0.15 mg/kg

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18
Q

Panc Onset

A

2-4 minutes

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19
Q

Panc Maintenance dose

A

.02 mg/kg

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20
Q

Best drug for renal and liver failure patients

A

Cis
Atracurium is also but produces histamine

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21
Q

Succ ED95

A

0.3 mg/kg

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22
Q

Vec duration

A

30-45 minutes

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23
Q

Panc ED95

A

0.075 mg/kg

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24
Q

Vec ED95

A

0.05 mg/kg

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25
Q

Panc duration

A

45-90 min

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26
Q

Cis intubating dose

A

0.1 - 0.2 mg/kg

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27
Q

Cis ED95

A

0.05 mg/kg

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28
Q

Cis onset

A

2-4 minutes

29
Q

Cis Maintenence dose

A

0.02 mg/kg

30
Q

Cis duration

A

45-60 min

31
Q

Cis metabolism

A

Hofmann
Laudanosine

32
Q

Atracurium intubating dose

A

0.5-0.6 mg/kg

33
Q

Atracurium ED95

A

0.15 mg/kg

34
Q

Atracurium onset

A

2-3 minutes

35
Q

Atracurium maintenance dose

A

0.1 mg/kg

36
Q

Atracurium duration

A

30-60 minutes

37
Q

Atracurium metabolism

A

Hofmann
Laudanosine

38
Q

Mivacurium intubating dose

A

0.15-0.25 mg/kg

39
Q

Mivacurium ED95

A

0.08 mg/kg

40
Q

Mivacurium onset

A

2-3 minutes

41
Q

Mivacurium maintenance dose

A

0.1mg/kg

42
Q

Mivacurium duration

A

15-20 minutes

43
Q

Mivacurium metabolism

A

pseudocholinesterase

44
Q

Neostigmine dose for 2 twitches

A

0.07 mg/kg

45
Q

Neostigmine dose for 3-4 twitches

A

0.04 mg/kg

46
Q

Neostigmine dose range and max dose

A

0.02-0.07 mg/kg
max 5mg

47
Q

Neostigmine onset

A

5-15 minutes

48
Q

Neostigmine duration

A

45-90 minutes

49
Q

Neostigmine metabolism

A

50% renal 50% hepatic

50
Q

Edrophonium dose

A

0.5-1 mg/kg
Need 4 twitches back to give!

51
Q

Edrophonium onset

A

1-2 minutes

52
Q

Edrophonium duration

A

30-60 minutes

53
Q

Edrophonium metabolism

A

75% renal
25% hepatic

54
Q

Pyridostigmine dose

A

0.1-0.3 mg/kg

55
Q

Pyridostigmine onset

A

10-20 minutes

56
Q

Pyridostigmine duration

A

60-120 minutes

57
Q

Pyridostigmine metabolism

A

75% renal
25% hepatic

58
Q

Suggamadex dose for 2 TOF twitches

A

2 mg/kg

59
Q

Suggamadex dose for PTC 1-2

A

4mg/kg

60
Q

Suggamadex dose for profound block/3-5 minuntes after NMBDs

A

16 mg/kg

61
Q

Dose of roc if it’s been 5 minutes since 4mg/kg of suggamadex

A

1.2 mg/kg

62
Q

NMB drug and dose if it’s been 4 hours since reversal with suggamadex

A

0.6mg/kg Roc
or
0.1mg/kg vec

63
Q

Dosing for glyco

A

0.01-0.02 mg/kg
0.2 mg per 1 mg of neostigmine

64
Q

Onset of glyco

A

2 min

65
Q

Duration of glyco

A

2-4 hours

66
Q

Dose of atropine with edrophonium

A

7 mcg/kg

67
Q

Dose of atropine with neostigmine

A

0.015 mg/kg

68
Q

Onset atropine

A

1-2 min

69
Q

Duration atropine

A

1-2 hours

pharmacodynamics anesthesia (4 decks)

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