NIPT Flashcards
1
Q
When?
A
Present in maternal blood as early as 5 weeks, and reaches optimal level for analysis at 10 weeks LO 1999
2
Q
Routine screening: 18+21 >99% effective 0.1% FPR
A
Krypos et al (2012)
3
Q
Limitations
A
Vanishing twin, placental mosaicism, detect maternal problem, low cffDNS conc (BMI)
4
Q
Not diagnostic, patient declined amnio in favour of NIPT, FP
A
Smith et al (2013)