NICU Flashcards
Elevated AFP
Hint RAIN
R. Renal (nephrosis, agenesis, pckd)
A. Abdominal wall defects
I. Incorrect dates/ multiple pregnancies
N. Neuro (ancephaly or spins bifida)
RAIN elevates the level of AFP reservoirs
Low AFP
Trisomy 21- downs
Trisomy 18- Edwards
The most common cause of fetal bradycardia is…….
Heart block
May be seen in maternal lupus
What is the difference in fetal medicine between a non stress test and a contraction stress test?
Non stress test- measures spontaneous fetal movements and HR
Measures fetal autonomic nervous system integrity
Contraction stress test- measures fetal HR in response to contractions
Measures uteroplacental insufficiency and tolerance of labor
Positive= late deceleration after 50% of contractions
What are the 2 components of a BPP (biophysical profile)
Non stress test
US
What are the 5 things and US measures in a BPP
Fetal movement Reactive HR Breathing Tone Volume of fluid
What’s the difference between apnea and periodic breathing
Apnea lasts for longer than 20s
2 treatments for apnea of prematurity
Caffeine
Theophylline
What is primary apnea and how do you treat it?
See this post delivery
Gasping with increased depth and RR followed by apnea
Treat with stimulation
Also blow by o2
What is secondary apnea and how do you treat?
Occurs if primary apnea does not resolve
Rule of thumb is greater than 30s of apnea after delivery
More gasping apnea
Oxygen and stimulation do not help
Treat with PPV
How much pressure is needed to inflate the lungs with the first breath?
60 mmHg
Definition of TTN
Tachypnea in otherwise health infants caused by retained fetal fluid
See with CS babies
Diagnosis of exclusion
Presents in first few hours of life
Tachypnea >60
Retractions, nasal flaring, grunting
What does the X-ray of TTN look like
Fluid in the inter lobar fissures
Increased pulmonary markings
How long does TTN last?
72hrs
TTN treatments
NPO
Close monitoring
HIE definition/head cooling requirement
Apgar <5 at 10 min
Apgar <3 for longer than 5 min
pH <7
Base deficit >16
> 36 wks
< 6 HOL
Metabolic disturbances seen in HIE
NORMAL anion gap Elevated ammonia Lactic acidosis Hypoglycemia Hypocalcemia Hyponatremia pH <7
At what weeks of development does surfactant surge?
33-36 wks
CXR in RDS
GROUND GLASS
granular opacifications
air bronchograms
obscure heart and diaphragm borders
Think of this when there is temperature instability in an infant
INFECTION!
GBS pna
what happens in children with RDS & hyperbilirubinemia
higher risk of kernicterus!
increased risk of RDS with…. (5)
1- premies 2- IDM---> can interfere with the accuracy to L:S 3- CS deliver 4- birth asphyxia 5- surfactant B deficiency
decreased risk of RDS with…. (3)
1- PROM
2- antenatal steroids
3- L:S >2
start on vent if pH…. and PCO2…..
<7.2
>60
what do you want your PO2 to be with RDS babies on vents/ECMO/HFOV
50-70 mmHg
what is the difference between prophylactic and rescue surfactant
1- prophylactic- given in first 2 HOL to babies <30 wks
2- rescue- given later after dx RDS made
what does surfactant do to the following….
____ O2 requirement
____ inspiratory pressure
____ lung compliance
decrease
decrease
improve/increase
ECMO criteria
reversible lung dz <10-14 day duration
failure of other methods
- no systemic or intracranial bleeding
- no CHD
PIE definition
pulmonary interstitial emphysema
cause of deterioration of babies with RDS on vents
air leaks into the interstitium
can end up as pneumothorax
what is the cause of BPD
bronchopulmonary dysplasia/chronic lung disease
arrest of nl lung development in premature infants
when does bilirubin peak in term infants? in premies?
3-5 DOL
5-7 DOL
CXR findings with BPD
GROUNG GLASS
diffuse opacities
cystic areas with streaky infiltrates
when are mothers screened for GBS?
35-37 weeks GA
when do you see…
early onset GBS?
late onset GBS?
late, late onset GBS?
first 7 days after birth
~4 weeks after birth (but up to 90d)
up to 6 mos after birth (premies)
the difference between mothers with babies with GBS vs listeria
GBS mom often asymptomatic
Listeria mom often with flu-like illness
when it’s OK not to tx babies with GBS+ mothers
mom adequately tx
OR
CS prior to ROM
*if mother not adequately tx, but asym and baby asym, monitor baby for 48HOL
Erb’s palsy
C5-7
waiter’s tip- adducted, internally rotated, wrist and fingers flexed
grasp intact
with a baby with Erb’s palsy and respiratory distress- think of this
Phrenic nerve palsy
C3-5 keeps the diaphragm alive
klumpke palsy
C8-T1
claw hand
can be associated with Horners syndrome
cord that stays attached >1 month… think of this (2)
1- LAD - leukocyte adhesion deficiency
2- low WBC
further work up for infant with single umbilical artery
Renal US
can have associated renal dz
definition of SGA
<10th percentile weight for GA
< 2500 g
definition of LGA
> 90th percentile weight for GA
>3900 g
Term baby
38-42wks
normal scalp pH
> 7.25
hint for knowing MAP (mean arterial pressure) in premies
MAP should not be lower than corrected GA
definition of VLBW
<1500g
What does CXR look like with meconium aspiration
areas of atelectasis and areas of hyperinflation
can lead to pneumothorax (10-20%)