nibs Flashcards

0
Q

Pazopanib/sorafenib/Sunitinib

SE’s

A

Pazo: Hepatotoxic/GI perf/Hemorrhage/hypertension
Soraf: Hemorrhage/htn
Sun: Hand/foot/skin

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1
Q

Pazopanib/sorafenib/Sunitinib

Receptor

A

VEGF-R

PDGF-R

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2
Q

Erlotinib/Gefitinib

Receptor

A

EGFR

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3
Q

Erlotinib/Gefitinib

SE’s

A

Cardiomyopathy
Pneumonia
Teratogen

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4
Q

Bortezomib

Receptor

A

26s proteosom

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5
Q

Bortezomib

SE’s

A

Thrombocytopenia
anemia
neuropathy

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6
Q

Vorinostat

Receptor

A

HDAC

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7
Q

Vorinostat

SE’s

A

Drug/drug
Pulmonary Embolism/DVT/thrombocytopenia/anemia
Diarrhea

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8
Q

Lopatinib

Receptor

A

EGFR

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9
Q

Lapatinib

SE’s

A

Hepatotoxic

Cardiotoxic

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10
Q

Imatinib

Receptor

A

BCR-ABL

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11
Q

Imatinib

SE’s

A

Cardiomyopathy
Teratogen
Edema
BMS

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