Neutropenic and Maternity Sepsis

Question 1

Define neutropenia

Answer 1

Neutrophils less than 1.5*109

Question 2

Causes of neutropenia

Answer 2

Malignancy( usually 7-10 days after chemo)
Autoimmunitu (RA or it’s ttt)
Vitamin B12 deficiency

Question 3

Define neutropenic sepsis

Answer 3

Any fever of higher than 38 or any signs of sepsis in a person with neutrophil count of less than 0.5

Question 4

How to manage neutropenic sepsis

Answer 4

IV pipercillin and tazobactam in secondary and tertiary hospital even for those with suspected neutropenic sepsis

Question 5

True or false: Longer and higher of antibiotics are required to treat neutropenic sepsis

Answer 5

True

Question 6

What is used for neutropenic sepsis prophylaxis?

Answer 6

Fluoroquinolone

Question 7

Name the poor prognostic factors of neutropenic sepsis

Answer 7

Old age, hematological malignancies, gram negative sepsis