neurotransmitters TTSTB Flashcards
what are neurotransmitters?
Chemical messengers that influence behavior and cognition
How do neurotransmitters interact with neurons?
they can increase (excitatory) or decrease (inhibitory) the changes of a neuron being activated.
serotonin
function: mood regulation, attachment, appetite, sleep
low levels: depression, anxiety, and aggression
high levels: serotonin syndrome
STUDY ON NEUROTRANSMITTERS: SEROTONIN
Passamonti et al, 2021
aim: to see what effect reduced serotonin has on the prefrontal cortex when exposed to threat
- drink reduce serotonin
- FMRI machine
- angry, neutral, and sad faces
- reduced function in the PFC when viewing angry faces
- serotonin is linked with impulsive aggression
glutamate
function: learning and memory
low levels: concentration problems and mental exhaustion
high levels: neuron damage, neurodegenerative disease
ketamine
what: glutamate antagonist
use: medically to treat PTSD
block receptors
STUDY ON NEUROTRANSMITTERS: GLUTAMATE
Feder et al 2014
aim: to test the effectiveness of ketamine in reducing PTSD symptoms
- 41 participants with PTSD: ketamine vs midazolam
- ketamine worked better: antagonist of glutamate (excitatory neurotransmitter), inhibiting its work in the amygdala.