Neurotransmitters and receptors Flashcards
cholinergic neurons
Bind with acetylcholine
adrenergic neurons
norepinephrine or epinephrine
Presynaptic, autonomic neurons are all
cholinergic
Sympathetic, postganglionic neurons
are adrenergic
parasympathetic, postganglionic neurons are
cholinergic
cholinergic receptors are characterized as
Muscarinic or nicotinic
Muscarinic
when acetylcholine binds it initiates a G protein mediated response
Excitatory or inhibitory
Regulates glands, smooth muscles, heart rate
nicotinic
activated by nicotine
acetylcholine binding equals fast induction of excitatory post synaptic potential
Nicotine binding equals increased task performance and attention
what is the common sympathetic postganglionic neurotransmitter
norepinephrine
epinephrine and norepinephrine are released directly into the blood by
the adrenal medulla
Receptors that bind epinephrine and norepinephrine are adrenergic receptors
adrenergic receptors
bind norepinephrine or epinephrine
two groups alpha and beta with subtypes for each
adrenergic receptors are mostly found
Peripheral smooth muscle
the heart
bronchial smooth muscle
Which receptors are mainly found in the bronchi smooth muscle
beta 2 adrenergic receptors
Bronchial tree dilation for greater airflow
Skeletal muscle arterial walls have primarily which receptors
alpha adrenergic receptors
Norepinephrine binding equals vasoconstriction
Important for regulating blood pressure
blood pressure can be decreased by using Alpha blockers to
Block the norepinephrine binding in the blood vessel.
(vasodilation, decrease blood pressure)
beta blockers are used to treat high blood pressure by
Preventing sudden increases in the heart rate and decrease the probability of arrhythmic contractions of the heart
(cardiac arrhythmias, MI, )
Decreases heart rate and contractility
beta 2 agonists prevents
prevents airway constriction, asthma, and COPD
Primary role of the sympathetic nervous system
Maintain optimal blood supply to the organs
other important roles of the sympathetic nervous system
fight or flight response induced by fear
Pupil dilation
bronchodilation
Cardiac acceleration
Digestion inhibited
Piloerection
glucose release stimulated
Systemic vasoconstriction
body temperature regulation from sympathetic activity
epinephrine is released by the adrenal medulla and increases metabolic rate
The byproduct is heat
sympathetics control the diameter of blood vessels, sweat glands, secretion, and piloerection
Primary function of the parasympathetic nervous system
Energy conservation and storage
other functions of the parasympathetic nervous system
Rest and digest
Pupillary constriction cranial nerve three
Bronco constriction cranial nerve 10
Decreased heart rate cranial nerve 10
Digestion stimulated
Salivation cranial nerves, seven and nine
Lacrimation cranial nerve seven
Intestinal vasodilation
Sacral efferents- bowel and bladder emptying and erection