Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Neuro Path (2nd Year) > Neurotransmitters > Flashcards

Neurotransmitters Flashcards

1
Q

Glutatmante AMPA ionotropic/ metabtropic

A

ionotropic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

How does AMPA work

A

Na fast activation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

NMDA is ionotrpic or metabotropic

A

ionotrpic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

how does NMDA work

A

Mainly Ca, but some Na and K, Ca signaling cascade

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

how is NMDA regulated

A

voltage gated dependent Mg block and requires glycine to be activated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what is NMDA’s function?

A

synaptic plasticity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what are 2 NMDA antagonists

A

PCP ketamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Kainate is a receptor for which NT

A

glutamate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

how does Kainate work

A

Na, slow activation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

how do Metabotropic glutamate recpetors work

A

g proteins to alter Ca or adenyl cylase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What function do metabotropic gluatmate receptors have?

A

memory

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Is GabaA ionotrpic or metabotropic and how does it work

A

ionotropic, Cl-, hyperpolarizing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

GabaA g subunit does what

A

increase affinity for GABA and increase frequency of opening of chloride channel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

GabaA b subunit does what and used with which kind of drugs

A
  • increase affinity for GABA and incrase frequency of opening of chloride channel
  • use primarily w/ anesthesia and seizure disorders
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

GabaB is ionotropic/metabotropic and works how

A

Metabotropic

stimulate K and close Ca, so hyperpolarizing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

GabaB what drugs is an agonist

A

baclofen which is used for ALS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Gaba C aka A-p is ionotrpic or metabotropic, where is it expressed, and what drugs is it acted on by

A

ionotropic
retina, spinal cord, pituitary
not modualted by benzos, barbs or baclofen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Nicotonic acetylcholine receptors are ionotropic/ metabotropic

A

ionotrpic

19
Q

What are 3 agonists for nicotonic acetylcholine receptors

A

nicotine, epibatidine, choline

20
Q

muscarinicacetylcholine receptors are ionotropic/ metabotropic

A

metabotrpic, G coupled

21
Q

Where are M2 acetylcholine receptors found

A

heart

22
Q

where are M3 acetylcholine receptors found

A

smooth muscles

23
Q

What is atropine

  • which subunit
  • 2 indications
A

ACh M1-5 antagonists

mydriatic

24
Q

What is Scopolamine

  • which subunit
  • 2 indications
A

M1 antagonist
motion sickness
salivation

25
Q

muscarine is an agonist for which subunits

A

M1-2

26
Q

carbachol is what

A

muscarinic agonist on M1-5

27
Q

pilocarbine is what

- used for what

A

muscarinic agonist on M3

used for glaucoma

28
Q

serotonin and melatonins are what class of monoamines?

A

Trptamines

29
Q

Steps in Epinephrine synthesis

A

L-tyrosine , L-DoPa, Dopamine, Norepi, epinephrine

30
Q

Serotonin structure

A

look it up

31
Q

which receptors are in D1 family of dopamine receptors

A

d1 , d5

32
Q

is d1 family of dopamine receptors excitatory or inhibitory

A

excitatory

33
Q

where is norepi produced in the brain (2)

A

Locus Coeruleus, Caudal Raphe Nucleus

34
Q

Norepi increase via clonidine is used for waht 4 indications

A

neuropathic pain, opioid detox, ADHD, tourette’s

35
Q

where is serotonin produced

A

raphe nucleus

36
Q

serotonin involved in

A

anger, aggression, mood, sleep, sexuality, appetite, pain

37
Q

action of CB1

A

inhibits GABA and Glutamate release

38
Q

what is anandamine

A

endogenous CB1 agonist that attenuates pain

39
Q

THC is an agonist of CB1 or CB2

A

1

40
Q

opioid receptors are ionotropic or metabotrpic

A

metabotropic

41
Q

what does PCP stand for

A

phencyclidine

42
Q

effector pathway for norepi

A

intracellular mediation of cAMP

43
Q

do amphetamines affect serotonin

A

yes

44
Q

serotonin used for what clinically (5)

A

depression, migraine, anxiety, sleep disorders, and pain

Neuro Path (2nd Year) (6 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions