Neurotransmitter Review Flashcards
Which brain system produces NE, Serotonin, DA, Ach?
Reticular Activating System
What are the major target areas for RAS NTs like NE, serotonin, DA and ACh?
Nuclei in:
Basal Forebrain
Limbic System
Cerebral Cortex
NT activity relies on what three variables to achieve overall function?
brain region + NT input + density of receptors = psych function
Which NT?
Cortex/Stem/Hypothalamus:
Arousal, sleep/wake cycles
Consciousness
Cortex:
Attention
Cortex/Limbic:
mood
learning
NE
Which NT is produced in the locus coeruleus?
NE
The below are d/os related to imbalance of which NT?
ADD
Mood d/o (bipolar)
GAD, PTSD
Abuse: Psychostimulants
NE
Which NT is produced in the raphe nuclei in the brianstem?
5HT (Serotonin)
Which NT has the follow forebrain effects?
Limbi: mood
Cortex, thalamus: Sensation & perception
Hypothalamus: circadian rhythm & appetite
5HT (Serotonin)
Which NT has the below characteristic d/os?
- Mood d/o
- Impulse control d/o
- OCD
- Anxiety d/o (social, generalized)
- Eating d/o
- Drugs of abuse: hallucinogenics
Serotonin
Which NT is produced in the substantia nigra and the VTA of the midbrain?
DA
Which NT has the following targets and effects?
- SN to basal nuclei
a. Motor control - VTA to limbic system and cortex
a. Reward, reinforcement, cognition
DA
The below are d/os related to _____ imbalance…
- Psychotic d/o
- SUD
- Movement d/o
a. Parkinson’s - Cognitive d/o
a. Delirium - Mood d/o (moderate assoc.)
DA
This NT is produced in the medial spetum and nucleus basalis of meynert of the basal forebrain…
ACh
Which NT has the following forebrain targets?
Hippocampus, cortex
ACh
ACh imbalance is associated with what two classes of disorders?
dementia and neurocognitive d/o
