Neurotransmission Flashcards

1
Q

a-methyltyrosine

A

competitive inhibitor of tyrosine hydroxylase

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2
Q

a-methyldopa

A

produces a-methylNA which is an antihypertensive agent

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3
Q

atenolol

A

b1-adrenoceptor antagonist

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4
Q

atracurium

A

non-depolarising neuromuscular blocking agent

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5
Q

atropine

A

muscarinic antagonist

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6
Q

boTX-A to G

A

Botulinum Toxins (A-G); Cleaves various SNARE proteins

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7
Q

Caffeine

A

Competitive antagonist for A1 receptor, also inhibits phosphodiesterases

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8
Q

Carbidopa

A

Inhibitor of DOPA Decarboxylase (DDC)

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9
Q

Cevimeline

A

Muscarinic M3 receptor agonist

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10
Q

Cocaine

A

Inhibitor of Uptake 1 (NET/SERT/DAT)

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11
Q

Dexamfetamine

A

Indirectly-acting sympathomimetic amine

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12
Q

Dobutamine

A

b1-adrenoceptor selective agonist

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13
Q

Edrophonium

A

short acting anticholinesterase

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14
Q

Ephedrine

A

mixed-acting sympathomimetic monoamine

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15
Q

Entacapone

A

COMT inhibitor

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16
Q

Hexamethonium

A

Use-dependent blocker of ganglionic nicotinic receptor

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17
Q

Imipramine

A

Tricylic antidepressant inhibits NET

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18
Q

Indacaterol

A

selective b2-adrenoceptor agonist (ultra long acting)

19
Q

Ipratropium

A

short-acting muscarinic antagonist (SAMA)

20
Q

Isoprenaline (ISO)

A

B-adrenoceptor selective agonist

21
Q

L-DOPA

A

DOPA decarboxylase (DDC) substrate

22
Q

Mirabegron

A

B3-adrenoceptor selective agonist

23
Q

Nebivolol

A

B1-adrenoceptor antagonist

24
Q

Neostigmine

A

Medium acting anticholinesterase

25
Q

Phenoxybenzamine

A

Irreversible a-adrenoceptor antagonist and NET/EMT inhibitor

26
Q

Phenylephrine

A

a1-adrenoceptor selective agonist

27
Q

Pilocarpine

A

muscarinic agonist

28
Q

Pralidoxime

A

AChE reactivator, used as an antidote for organophosphate poisoning

29
Q

Prazosin

A

a1-adrenoceptor selective antagonist

30
Q

Propranolol

A

non-selective b-adrenoceptor antagonist

31
Q

Resperine

A

Inhibits vesicular monoamine transporter (VMAT)

32
Q

Regadenoson

A

selective A2a adenosine receptor agonist

33
Q

Rocuronium

A

Non-depolarising neuromuscular junction blocking agent

34
Q

Salbutamol

A

B2-adrenoceptor selective agonist (short acting)

35
Q

Salmeterol

A

B2-adrenoceptor selective agonist (long acting)

36
Q

Solifenacin

A

Muscarinic M3 receptor antagonist

37
Q

Suramin

A

Antagonist for all P2X (and some P2Y) receptors

38
Q

Suxamethonium (succinylcholine)

A

Depolarising neuromuscular blocking agent

39
Q

Tamsulosin

A

a1a-adrenoceptor selective antagonist

40
Q

TeNT (tetanus toxin)

A

cleaves synaptobrevin in specific inhibitory interneurons in the CNS

41
Q

Tiotropium

A

Long-acting muscarinic antagonists (LAMA)

42
Q

Xylazine

A

selective a2-adrenoceptor agonist

43
Q

xylometazoline

A

non-selective a-adrenoceptor agonist

44
Q

Yohimbine

A

a2-adrenoceptor selective antagonist