Neurosurgery Flashcards

1
Q

How do vascular neurologic problems present?

A
  • Sudden onset
  • w/o headache when they are occlusive
  • w headache when they are hemorrhagic
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2
Q

How do brain tumors present?

A
  • Constant, progressive and severe headache, sometimes worse in the morning
  • Timetable of months
  • As intracranial pressure increases, blurred vision and projectile vomiting occur
  • Functional deficits are seen when tumor presses on an area assoc. w a particular function
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3
Q

How do infectious neurological problems present?

A
  • timetable of days/weeks
  • An identifiable source of infection is commonly found in the pt’s hx
  • -Metabolic problems develop w/in hrs or days and affect the whole CNS
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4
Q

How long do degenerative diseases take before presenting sx?

A

-They have a timetable of years

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5
Q

What is an Transient Ischemic Attack (TIA)?

A
  • Sudden, transitory losses of neurologic function, w or w/o headache, that resolve spontaneously leaving no sequela
  • Specific sx depend on area affected, which is related to the vessels involved
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6
Q

What s the most common origin of a TIA?

A

->= 70% stenosis of internal carotid, or ulcerated plaque at carotid bifurcation

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7
Q

What is the significance of TIA’s?

A

-They predict strokes, which can be prevented with timely elective carotid endarterectomy

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8
Q

What is the work up of TIA’s?

A
  • Duplex studies

- Surgery indicated if the lesions are found at the locations that explain the neurologic symptoms

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9
Q

What alternative tx can be used for TIA’s?

A

-Angioplasty and stent can be done if a filter is first deployed to prevent embolization of debris

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10
Q

How does an Ischemic stroke present?

A

-Sudden onset w/o headache but w neurologic sx present for >24 hrs, leaving permanent sequela. Not amenable to revascularization (except for very early strokes)

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11
Q

What is a hemorrhagic infarct?

A

-It can be a complication of an ischemic infarct when blood supply to that area of the brain is suddenly increased.

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12
Q

How are ischemic strokes managed?

A
  • Vascular studies are done to identify lesions that might produce another stroke and prevent it.
  • For existing infarcts, the only management available is assessment with CT and rehabilitation
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13
Q

How are early strokes treated?

A
  • CT scan to r/o existing infarcts or presence of hemorrhage

- t-PA IV within 90 min and up to 3 hrs after onset of sx

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14
Q

In what patient is a hemorrhagic stroke commonly seen?

A

-Uncontrolled hypertensive with sudden onset of headache and goes son to develop neurologic sx

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15
Q

How is a hemorrhagic stroke managed?

A
  • CT scan to evaluate location and extent

- Tx to control hnt and focused on rhabilitation

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16
Q

A patient c/o extremely severe headache of sudden onset like no other ever experienced before (Thunderclap: sudden, severe, singular) is suspicious for…?

A
  • Subarachnoid bleeding from intracranial aneurysms
  • In many cases the pt is not salvageable
  • Patient may be sent home by mistake bc there is likely no neurologic findings (Blood in the subarachnoid space, so there’ snot hematoma pressing on the brain)
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17
Q

What are two red flag sx of subarachnoid aneurysm bleeding?

A

-Meningeal irritation and nuchal rigidity

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18
Q

What happens to patients who are not recognized to have a bleeding subarachnoid aneurysm?

A

-IF they survive, they may return in 10 days with a subsequent (and likely more severe) bleed.

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19
Q

What is the workup for subarachnoid aneurysm bleed?

A
  • CT scan to look for bleeding
  • Arteriogram to locate aneurysm
  • Surgical clipping or endovascular coiling may be performed
  • NOTE: Spinal tap looking for blood may be done, but should never be the first test. Always do CT first
20
Q

What is the presenting history of Brain tumors?

A
  • Progressively increasing headache for several months, worse in the mornings
  • Eventually: accompanied by signs of increased intracranial pressure
21
Q

What are sx of increased intracranial pressure?

A
  • Blurred vision
  • Papilledema
  • Projectile vomiting
  • Bradycardia (extreme d/t Cushing reflex)
  • Hypertension (Extreme d/t Cushing reflex)
22
Q

Which is the preferred study to visualize brain tumors?

A

-MRI bc it gives better details

23
Q

How is increased intracranial pressure treated?

A

-High-dose steroids like dexamethasone (Decadron) while awaiting for surgical removal

24
Q

What is a “silent area”?

A

An area of the brain where brain tumors can grow without providing any clue as to their location (no neurological sx)

25
Q

How can brain tumors be localized?

A

Some tumors can be localized by specific neurological effects depending on which area of the brain they affect

26
Q

How do tumors pressing on the lateral side of the brain present?

A

-Motor strip and speech center may be affected producing sx in the opposite side of the body

27
Q

How do tumors at the base of the frontal lobe present?

A

-They can cause inappropriate behaviors, optic nerve atrophy on the side of the tumor, papilledema on the other side and anosmia (Foster-Kennedy Syndrome)

28
Q

How do Craniopharyngioma present?

A

-In youngsters who are short for their age, w bitemporal hemianopsia, and calcified lesion above the sella on x-rays

29
Q

how do prolactinomas present?

A

-Amenorrhea and galactorrhea in young women

30
Q

What is the work up for prlactinomas?

A
  • r/o pregnancy
  • r/o hypothyroidism
  • determine prolactine level
  • MRI of sella
31
Q

What is the treatment of prolactinomas?

A
  • Bromocriptine

- Transnasal or trans-sphenoidal surgical removal for those wishing to get pregnant or who fail medication

32
Q

What are sx of acromegaly?

A
  • Huge tongue, hands, feet and jaws

- hypertension, diabetes, sweaty hands, headache and a hx of wedding bands of hasts that no longer fit

33
Q

What is pituitary apoplexy?

A

-Bleeding into a pituitary tumor, destroying the pituitary gland

34
Q

What are the sx of pituitary apoplexy?

A
  • Starts w sx of pituitary tumor: headache, visual loss, endocrine problems
  • Then the acute bleeding episode: severe headache, deterioration of remaining vision w bilateral pallor of the optic nerves d/t compression by hematoma, and stupor w hypotension d/t destruction of the pituitary gland
35
Q

What is the management of pituitary apoplexy?

A
  • Urgent steroid replacement as well as other hormones

- MRI or CT can show extent of the problem

36
Q

What causes loss of upper gaze and “sunset eyes” sign?

A

-Tumors of the pineal gland
-Sunset eyes: The sclera are visible between the upper eyelid and the iris-
Part of Parinaud syndrome

37
Q

Where are brain tumors in children commonly located?

A

-The posterior fossa

38
Q

What sx can be seen in brain tumors in children?

A
  • Cerebellar sx: stumbling around, central ataxia

- -Severe headache relieved by assuming the knee-chest position

39
Q

What can cause similar sx to brain tumors, but in a much shorter timetable?

A
  • Brain abscesses (they are a space-occupying lesion)

- They develop sx in a week or two

40
Q

What are the sx of brain abscesses? How are they managed?

A
  • Fever, obvious source of infection nearby (usually)
  • Typical appearance on CT, so MRI is not needed
  • They require resection
41
Q

How do brain abscesses look on CT? (Not from Pestana’s, but I figured it might be useful)

A

-Ring of iso / hyperdense tissue, typically of uniform thickness
-Central low attenuation (fluid / pus)
surrounding low density (vasogenic oedema)
-Ventriculitis may be present, seen as enhancement of the ependyma
-Obstructive hydrocephalus will commonly be seen when intraventricular spread has occurred

42
Q

What does a patient with severe sharp shooting pain “like a bolt of lightning” after touching a specific area and lasting about 60 seconds have?

A

-Trigeminal neuralgia (tic douloureux)

43
Q

How do patients with trigeminal neuralgia present?

A
  • Normal neurologic exam

- Unshaven area in the face (trigger zone)

44
Q

How is trigeminal neuralgia managed?

A
  • MRI to r/o organic lesions
  • Anticonvulsants
  • Radiofrequency ablation can be done if medication fails
45
Q

Constant, burning, agonizing pain that does not respond to usual analgesics and develops several months after a crushing injury:

A
  • Reflex sympathetic dystrophy (causalgia)
  • Pain aggravated by slightest stimulation of the area
  • Extremity is cold, cyanotic and moist
46
Q

How is causalgia treated?

A
  • Dx with successful sympathetic block

- Cured with surgical sympathectomy

47
Q

What are the 3 signs of cushings reflex? When does cushings reflex occur?

A
  • htn, bradycardia, respiratory depression

- sign of increased intracranial pressure