Neuroscience and Behavior - Week 1 Flashcards
Neuron
Specialized cell that receives and transmits information
Glial Cells
Provide support and aid in information processing
Dendrites
Information Input Zone. Thicker than axons. Fuzzy due to dendric spines.
Stoma - Cell body
Information Integration Zone
Axon Terminals (Synaptic Bouton)
Output Zone. Swelling at the end of axons
Axon (Nerve Fiber)
Conduction Zone. Thinner. Surrounded by the myelin sheath in some mammals.
Multipolar neurons
They have many dendrites and appear a mess
Unipolar neurons
Single extension that branches into two after leaving stoma. Transmit touch information from body into spinal cord.
Bipolar Neurons
Single dendrite, single axon. Found in the sensory system (like vision).
Three components of a synaptic neuron
1) Specialized presynaptic membrane
2) Synaptic cleft
3) Specialized postsynaptic receptor
Synaptic vesicles
Contain molecules of neurotransmitter. Found in axon terminals.
Neurotransmitter
Special chemical used for communication between the presynaptic cell and the postsynaptic cell.
How does neurotransmitter transfer occur?
Synaptic vesicles in the axon terminal get excited by electrical signaling and transfuse into the synaptic cleft. Neurotransmitter gets released into the cleft and interacts/binds with that neurotransmitter’s specific receptor on the postsynaptic cell membrane. This causes activity in the postsynaptic cell. After the binding, neurotransmitter cells diffuse away - THEY DO NOT ENTER THE POSTSYNAPTIC CELL.
Axon Hillock
Cone-Shaped Enlargement on cell body from which an axon extends.
Anterograde Transport
Moves material toward axon terminals.
Axonal Transport
Moves organic material within the axon in both directions.
Retrograde Transport
Moves materials toward stoma for recycling.
Two functions of the axon
1) Rapid transmission of electrical signals along outer membrane (like a wire)
2) Slower transportation of substances within the axon (like a pipe)
Three types of research design
1) Somatic Intervention
2) Behavior Intervention
3)Correlation
Somatic Intervention
Alteration in the structure of brain or body to observe a change in behavior
Examples: Administering hormones, destroying brain regions.
Behavioral Intervention
The behavior of an organism is altered and the somatic changes in the body and/or brain are observed
Example: Placing male mice in a cage together and measuring their testosterone levels.
Correlation
Measure of how changes in one variable affect another variable
Examples: Extent to which memory alibi is related to a certain brain structure.
IT CANNOT ESTABLISH CAUSALITY!
Reductionism
Understanding complex systems by dissecting the simpler parts.
The Four Types of Glial Cells
1) Oligodendrocytes - Myelinate the axons of the brain and spinal cord
2) Schwann cells - Insulate axons with myelin in the rest of the body
3) Astrocytes - Star shaped and weave between blood vessels.
3)Microglial cells - Contain and clean sites of injury. Tiny and mobile