Neurorehabilitation Flashcards

1
Q

What does this define?

  • a process of active change
  • by which a person who has become disabled acquires the knowledge and skills needed
  • for optimal physical, psychological and social function.
A

The definition of rehabilitation!

a process of active change by which a person who has become disabled acquires the knowledge and skills needed for optimal physical, psychological and social function.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What classification does impairment, activity limitations and restrictions to life participation come under?

A

the international classification of functioning, disability and health (ICF)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

whaat does impairment, acitivty limitations and restrictions to life partificpation mean as part of the ICF (international classification of functioning, disability and health)?

A
  • imapirment
  • disorder of body structure or function e.g. anatomical or physiolgocial/pychological systems physiology
    • e.g. L MCA infarct resultin in aphasia w/1 word utterances
  • activity limitations
  • problems carrying out tasks or acitivities
    • e.g. unable to converse successfully with family
  • restrictions to life participation
  • problems participating in personally relevant aspects of life
    • e.g. unable to fulfil role of supportive mother to 5y.o daughter
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what are restorative vs comensatory techniques in neurorehab?

A
  • Restorative - assumes impairment is reversible
  • Compensatory - assumes impairment is irreversible
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What techniques are used to prevent impairments from worsening?

A
  • Passive range of movement
  • Stretching
  • Positioning to prevent contracture
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What does physical therapy and other techniques aim to achieve within neurorehab?

A

reorginisation of cortical maps –> recovery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What LT complications can arise from chronic neuro conditions seen in neurorehab (that need to be prevented)?

A

Physical

  • Spasticity
  • Contractures
  • neurogenic bladder and bowel dysfunction
  • Aspiration / chest infections
  • pressure sores
  • DVT

Mental

  • Pain
  • Depression
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What model of rehab is currently used?

A

Interdisciplinary model of rehab:

Interdisciplinary working involves a partnership between a team of health professionals and a client in a participatory, collaborative and coordinated approach to share decision making around health issues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How do you write a problems list in neurorehab?

A

you use the ICF by looking at

  1. what impairments they have,
  2. the acitivies they require assistance for/are unable to manage and
  3. the participation thay are unable to do/require assistance with
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is spascticity?

A

a velocity dependent increase in muscle tone

  • results from the disruption of the descending inhibitory modulation of alpha motor neurones
  • TF –> hyper excitability + abnormal processing of sensory input from affected muscles and their stretch receptors
  • a.g. the affected muscles sensory input is abnormal (stretch receptors) & the alpha motor neurones normal inhibitory modulation is disrupted –> spasticity
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what scale measures resistance during passive soft-tissue stretching and is used as a simple measure of spasticity?

A

the Modified Ashworth scale

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What complications can spasticity lead to?

A
  1. Muscle shortening
  2. Contractures
  3. Functional limitations due to limb deformity mechanics
  4. Associated spams & pain
  5. Pressure sores
  6. Low mood
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q
  • Baclofen
  • Tizanidine
  • Dantrolene
  • Benzodiazepines
  • Gabapentin
  • Cannabinoids

Are all what?

A

Anti-spastic medications

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Which anti-spastic drug is this?

  • Centrally acting antagonist that binds to GABA B receptors
  • May cause nausea, drowsiness, deranged liver function
  • Most commonly used and effective
A

Baclofen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which anti-spastic agent is this?

Has some anti-spastic properties and my be used as a single agent to treat neuropathic pain and spasticity

A

gabapentin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Which anti-spastic agent is this?

  • Centrally acting antagonist to GABA A receptors
  • Causes sedation so much more useful at night than in the daytime
A

benzodiazepine

17
Q

Which anti-spastic agent is this?

  • Suppresses calcium release from sarcoplasmic receptors therefore reducing the force of muscle contractions
    • May cause fatal hepatitis
    • Generally considered to be not as well-tolerated as baclofen
A

Dantrolene

18
Q

Which anti-spastic agent is this?

  • Centrally acting agonist action at alpha-2 adrenergic receptor sites
  • May cause sedation, visual hallucinations and deranged liver function
  • Generally considered to be not as well tolerated as baclofen
A

Tizanidine

19
Q

Which anti-spastic medication does this describe?

Nasal spray licensed for use in multiple sclerosis in patients suffering painful spasms

A

cannabinoids

20
Q

What use does orthotics have in spasticity?

A

Splints may be required to maintain joint position

21
Q

When may surgery be useful in spasciticty?

A

Surgical management may be required for

  1. contracture release and
  2. deformity correction
22
Q

nerve blockade may be useful as a permanent method of reducing muscle activity in a group of muscles e.g. spasticity

  • the susbtence is injected directly into nerves and denervation is caused by inflammation and subsequent fibrosis
  • There was much concern about dysasthesia (unpleasant sensation felt when touched) in the affected nerve but this does not seem to occur in clinical practice

What substance is used?

23
Q

What method of anti-spasmotic delivery is Most commonly used for non-functioning lower limbs when oral medications are not tolerated or sufficient ?

A

intra-thecal baclofen (between arach & pia)

  • Involves the insertion of an electronic pump into the abdominal wall
  • which delivers baclofen to the cerebrospinal fluid

Generally well tolerated most complications being infection and bleeding at the catheter insertion site

  • Test doses are required first
24
Q

What injection blocks the release of Ach at the NMJ and tf prevents muscle contraction, making it useful for focal spasticity….?

A

Botulinum toxin A!

  • however limited dose per procedure and number of injections per year
  • repeat injections maybe required
  • Peak effects at 3-4 weeks post injection with lasting effects up until 3-4 months
  • Very well-tolerated
    • rarely serial use may result in antibody formation
25
How does baclofen work?
Centrally acting antagonist that binds to GABA B receptors
26
What SE's may baclofen give?
May cause nausea, drowsiness, deranged liver function ---\> Most commonly used and effective
27
How does tizanidine work?
Centrally acting agonist action at alpha-2 adrenergic receptor sites ## Footnote *--\> Alpha 2 receptor agonists reduce central and peripheral sympathetic overflow and via peripheral presynaptic receptors may reduce peripheral neurotransmitter release.*
28
What are the SE of tizanidine?
May cause sedation, visual hallucinations and deranged liver function - Generally considered to be not as well tolerated as baclofen
29
How does dantrolene work?
Suppresses calcium release from sarcoplasmic receptors therefore reducing the force of muscle contractions
30
What are the SE of dantrolene?
May cause fatal hepatitis - Generally considered to be not as well-tolerated as baclofen
31
How do benzos work for spasciticy?
Centrally acting antagonist to GABA A receptors - Causes sedation so much more useful at night than in the daytime
32
What uses does gabapentin have in spasticity?
Has some anti-spastic properties and my be used as a single agent to treat neuropathic pain and spasticity
33
When is cannabinoid nasal spray licensed?
licensed nasal spray for use in MS patiends suffering painful spasms