Neuroradiology Review Flashcards
Dense MCA sign
early ischemia
Insular ribbon sign
early ischemia, insula hypodense
Loss of sulcal effacement
early ischemia
obscuration of lentiform nucleus/blurred BG
early ischemia
Best MRI sequence for blood?
Gradient
Can unilarteral PICA infarcts cross midline?
No, because vermian branches do not cross midline
Medial lenticulostriate
Supplied by M1
Lateral lenticulostriate
Supplied by A1
M2 and M3
M2 supplies area of sylvian fissure, M3 supplies cortical patietal region
Cortical border zone infarcts
Watershed, between ACA and MCA, or between MCA and PCA
Internal border zone infarcts
At the border between the lenticulostriate (A1/M1 tributaries) and the Deep penetrating MCA.
What to look at with Internal border zone infarcts?
Carotids
What to look for in border zone infarcts in general?
Carotids - makes sence, because this causes hypoperfusion.
“Lacunar”?
Lake like, in areas of BG, thalamus, white matter
Virchow-Robin Spaces (VRS)
Area where arteries enter brain parenchyma, can look like hypodense lacunes. Will be CSF intense on T2, black on flair.
PRES
Posterior Reversible Encephalopathy Syndrome
Is PRES vasgenic or cytotoxic
vasogenic
What does PRES look like on MRI
Should be PCA but can happen anywhere, hyperintense on FLAIR.
PRES associated with?
Hypertension, eclampsia, cyclosporine. Hypoperfusion –> vasogenic edema
Risk factors for venous thrombosis
Dehydration, pregnancy, hypercoaguability, mastoiditis
Presentation of venous stroke
Often presents as hemmoragic stroke in atypical location
How to find a venous stroke?
MRV
Glial
Astrocytoma, oligodendroglioma
Non-Glial
Meningioma, Schwannoma, Pituitary, Pineal, Lymphoma
Mets
Lung, Breast, Melanoma, Renal, Colon
What percentage of each?
1/3. 1/3. 1/3
Age under 2
Choroid plexus papilloma, Anaplastic astrocytoma, teratomas
Age under 10
Medulloblastoma, astrocytomas, ependymomas, craniopharyngiomas, gliomas.
Age adult
GBM, astrocytomas, meningiomas, oligodendrgliomas, pituitary, schwannomas
Common intra-axial supratentorial tumors in kids
astrocytoma, pleomorphic xanthoastrocytoma, PNET, DNET
Common intra-axial infratumors in kids
Juvenile pilocytic astrocytoma, PNET, ependymomas
Common intra-axial supratentorial tumors in adults
Gliomas, mets
Common intra-axial infratumors in adults
Mets, hemangioblastomas (METS ARE TOP 3 IN DIFFERENTIAL!)
Most adult intraaxial
MET
Most adult extraaxial
Meningioma, Schwannoma
Signs of extraaxial masses
CSF cleft, gray matter between the mass and white matter, brioad dural based, subarachnoid vessels displaced circumfrentially, Bony reaction.
Dural Tail
Meningioma, can see with schwannoma, but RARE
Enhancement of Intra/Extra axial
Extra axial should enhance, because NO BBB
Primitive neuroectodermal tumours (PNET)
Rare, from undifferentiated nerve cells (medullablastoma, pineal tumors)
What tumors cross midline?
GBM, meningioma, lymphoma, epidermoid cyst
How does GBM cross midline
IT infiltrates the corpus
How does Meningioma cross midline
Can spread long the meninges
How does Lymphoma cross midline
It is usually near the midline
How does epidermoid cyst cross midline
Via the subarachnoid space
Tumors seen in NFI
Optic glioma, astrocytoma
Tumors seen in NFII
Meningiomas, ependymomas
Tumors seen in Tuberous Sclerosis
Subependymal giant cell astrocytoma, ependymomas
Tumors seen in Von-Hippel Lindau
Hemangiomas
Tumors that are cotically based
Most tumors are white matter based. So cortical ones can be: oligodendroglioma, ganglioglioma, Dysembryoplastic neuroepithelial tumor (DNET)
Fat on CT HU?
It is -100
Fat on MRI?
Should have signal on both T1 and T2, however check fat sat and out of phase!
Fat satted tumors?
Lipoma, Dermoid Cysts, teratomas
What shows up high intensity on T1 that is not fat?
Melanin, Slow flow (IE hemangioma), blood (IE hematoma)
Calcified intraaxial tumors
Oligodendrogliomas almost always have calcification. However since astrocytomas are vastly more common, most calcified masses are astrocytomas (even though a small fraction have calcifications)
Calcifieed extraacxial tumors
Craniopharyngioma - Slow growing. Suprasellar, cystic squamous sell, in kids, rathke’s pouch
Cystic CNS lesions
Epidermoid, dermoid, arachnoid, neuroenteric. All are cystic. VRS can mimic
Appearance of cystic lesions on MRI
Intense on T2, isointense to CSF on most sequences because fluid.
High intensity on T1
Methhemoglobin, high protein, fat, cholesterol, melanin, slow flow.
What tumors show low intensity on T2
Dense tumors with high NC ratio: LYMPHOMA
Why does a lymphoma show up low intensity on T2
Becauese it has a high NC ratio
Melanoma metastesis
High T1, Low T2
When is restricted diffusion seen?
Abcesses, acute infarct, epidermoid cyst
What do tumors looks like on DWI
Most tumors do not cause restricted diffusion even in necrotic components. So most of the time the tumor will look hypointense.
Which type of tumors enhance?
Extra axial, because contrast does not have to cross the BBB.
What are some exaples of typical enhancing tumors
Meningioma, Schwannoma, Pituitary, Pineal
Does the pituitary have a BBB?
NO
Does the Ppineal gland have a BBB?
NO (Pineocytoma enhances!)
When will an intraaxial tumor enhance?
When the BBB is destroyed
What is an example of a tumor that breaks BBB?
GBM high grade, if it breaks BBB then it can enhance
What are some non-tumoral enhancing lesions
MS, infarctions
What lesions are expected to NOT enhance
Dermoid, Epidermoid, arachnoid cysts, low grade astrocytoma
What lesion has limited mass effect even when large, patchy enhancement, edema.
GBM - large infiltrative growth beyond MRI finidings
Ring enhancement
Mets, GBM, abcess (MAGIC DR)
Tumor arising from the Clivus
Chordoma
Tumors arising from the skull base
Chordoma, chondrosarcoma, fibrous dysplasia
Chordoma vs Chondrosarcoma
Chordoma midline, chondrsarcoma off-midline
Sellar and suprasellar lesions
Pituitary, cranio, meingio, chiasmatic glioma, any cyst, schwannoma, met
Name: Supracellar cystern, calcifications on CT, cystic component that shows no enhacement
craniopharyngioma
Common tumors in CP angle
Schwannoma, meningioma, cysts, mets
Intraventricular Tumors
Ependymoma, subependymoma, choroid plexis papilloma, central neurocytoma, colloid cyst, meningioma, giant cell astrocytoma
4th ventricular tumors in kids
Astrocytoma (pilocytic?), medulloblastoma, ependymoma
What do the saggital sinuses drain into?
Straight sinus
What does the vein of Galen Drain?
Drains deep central veins: thalamostriate, internal cerebral into straight sinus
What does the vein of Labbe drain?
temporal lobe into transverse sinus
What does the vein of Trolard drain?
Drains cortical to superior saggital sinus
Cause of venous thrombosis in neonate?
Shock, dehydration
Cause of venous thrombosis in children?
Sinusitis, mastitis
Cause of venous thrombosis in adults?
Coagulopathy, in women its OCP/pregnancy as highest risk factors
What is the dense clot sign?
Sometimes the clot shows up hyper dense on CT. Can see in straight, transverse, sigmoid, etc
What is the cord sign, and the dense vessel sign?
Same as dense clot sign
What is the empty delta sign?
Contrast CT scan shows a contrast void in the superior sagital sinus on axial. Looks like a delta with hypersense contrast around the central clot
First sign of venous thrombosis?
Edema, then possibly hemorrhagic conversion
What type of edema will VT cause?
Vasogenic
What is the distribution
Bilateral often
What does vasogenic edema look like
Finger-like
What if you see some vasogenic edema in temporal
Vein of Labbe
What if you see intensity on flair in thalamus and basal ganglia bilaterally? What does it mean?
BL means venous possibly, intensity is edema, location is Galen, or one of the other deep veins that Galen drains.
MR venograph types
Time of flight, phase contrast, contrast enhanced
Time of Flight venography
Uses the phenomenon of flow void, to create a signal intensity
Phase contrast venography
Development of phase shift due to flow, created an angio…
Contrast enhanced MRV
Uses T1 shortening of gado
What can mimic a venous clot?
Aracnoid granulation
Does MRV have pitfalls?
Lots. CTV is more reliable. Contrast MRV is better than the phase contrast or TOF MRV.
What does the quadragemial Cistern look like
Smiley face
What does the suprasellar cistern look like
Star of david
What are the three parts of the extradural ICA?
Cervical, petrous, cavernous
What is the Torcula?
Confluence of the sinuses
What structure pass through the optic canal
CNII, opthalmic artery, and vein
What structures pass through SOF
CNIII, IV, V1
What structures pass through IOF
V2
What are the three compartments of Orbit
Intraconal space, conal space (muscles), extraconal space
What is the blood supply to the globe
central retinal artery
What is more lateral, ICA vs IJV?
IJV
What are the divisions of the neck?
Supra, and infra hyoid neck
What are the four muscles of mastication
Medial/lateral pterygoid, masseter, temporalis
What term is used for cystic cavitation of an old infarct?
encephalomalacia
What looks like beads on string on CTA?
FMD
Five common causes of intraparenchymal hemmorage?
Amyloid, tumor, coagulopathy, venous infarct, AVM.
Where does spontaneous hemmorage occur
External capsule and basal ganglia and pons and cerebellum
Acute blood on CT? HU?
forty five
MAGICAL DRS
Mets, Abcess, Glioblastoma, Infarct, Contusion, AIDS, Lymphoma, Demylination, Resolving hematoma, Septic embolus
What are the two most common causes of SAH?
Trauma, Ruptured Berry aneurysm
What does an AVM look like on angiogram?
One large vessel feeding a tangle of abnormal vessels.
Two most common brain mets
lung and breast
What is the mnmonic for mets causing intracranial hemorrhage?
MRI CT
MRICT
Melanoma, RCC, insulinoma, choriocarcinoma, thyroid carcinoma
What is the treatment for a solitary met
surgical removal
What is the characteristic bony change for meningioma?
hyperostosis
What does meningioma look like on CT?
isodense, with homogenous enhacement and possible calcs, with hyperostosis
What does meningioma look like on MRI?
Isointense with bright enhancement
What is DISH
diffuse idiopathic skeletal hyperostosis. Anterior fusion flowing dyndesmophytes
Pineal region differential
Germ cell tumor, pinealocytoma, pinealblastoa, tecta glioma, meningioma, metastesis, aneurysm of the vein of galen.