Neuropsychopharmacology Flashcards
what is the decision about whether to use pharmacologic medications based on?
- To justify the use of medications, the child must first have a disorder or target symptoms with the potential for pharmacologic responsiveness.
- the child’s level of impairment must cross a threshold of severity such that failure to treat with medication, given all the potential risks, would cause more harm.
3, the child’s symptoms must be unresponsive or insufficiently responsive to nonpharmacologic interventions, or these interventions are not readily available in the community. - someone to monitor for SEs
Ritalin
Methylphenidate
Methylphenidate (MPH) non-competitively blocks the reuptake of dopamine and noradrenaline into the terminal by blocking the dopamine transporter (DAT) and noradrenaline transporter (NAT), increasing levels of dopamine and noradrenaline in the synaptic cleft.
Concerta
Methylphenidate, extended release
Dexedrine
Dextroamphetamine, immediate release
Vyvanse
Lisdexamfetamine
Adderall
Amphetamine
Strattera
Atomoxetine
Catapres
Clonidine
Guanfacine
Tenex
Intuniv
what are the signs of peak concentrations of stimulants in ADHD?
Effects associated with peak concentrations include dysphoria, anxiety, agitation, or the “zombie” effect (i.e., overfocused and passive). Rebound effects include overactivity, talkativeness, excitability, irritability, and insomnia.