Neuropsychology of Attention Flashcards
DSM-5 Diagnostic Criteria for ADHD
Five or more symptoms of inattention and/or ≥5 symptoms of hyperactivity/impulsivity for ≥6 months to a degree that is inconsistent with the developmental level.
* Several symptoms were present before the age of 12 years.
* Several symptoms must be present in ≥2 settings (e.g., at home, school, or work; with friends or relatives; in other activities).
* Symptoms interfere with or reduce the quality of social, academic, or
occupational functioning.
* Symptoms do not occur exclusively during the course of schizophrenia or another psychotic disorder and are not better
explained by another mental disorder
What is prevalence of ADHD per DSM 5
The DSM-5 indicates that about 5% of children have ADHD (APA,
2013).
Who is diagnosed more with ADHD (in children/adolescents), males or females?
- In children and adolescents, ADHD is more commonly diagnosed in males than females, with the sex ratio ranging from 2:1 to 10:1.
Interestingly, sex differences virtually disappear in adult populations
the sex ratio ranging from 2:1 to 10:1.
ADHD affects a greater proportion of female children and adolescents than is reflected in clinical practice.
ADHD impacts Social Functioning by
Children with ADHD tend to have fewer friends and less stable relationships than their same-age peers who do not have ADHD
Risk Factors for ADHD
Greatest risk factor is having a parent with ADHD
Low birth weight linked to development of ADHD symptoms
Low Apgar scores
lack of oxygen and neonatal
seizures are associated with later ADHD diagnoses
Exposure to Toxins
Brain anatomy difference with males and females in ADHD
Girls are more likely to present with predominantly inattentive
symptoms, which are believed to be housed greatly in the prefrontal
area, while boys more often present with combined inattentive and
hyperactive symptoms (i.e., ADHD—combined presentation) which is
reflected in the reduced surface area in both the prefrontal and the
premotor cortex.
Brain regions involved with attention
*Ventral anterior cingulate and dorsal anterior cingulate related to affective and cognitive executive control.
- Nucleus Accumbens, Putamen, Caudate form the frontostriatal circuit linking amygdala and cerebellum to frontal lobes.
- Imaging studies identify structural and functional abnormalities in all these areas of the ADHD brain.
- Dorsolateral prefrontal cortex is associated with working memory
- Ventromedial prefrontal cortex linked with complex decision making and planning
- Parietal cortex related to orientation of attention
-thalamus
Neurotransmitter Circuits in ADHD
Dopamine system (red) involved in planning and initiation of motor responses, activation, switching, reaction to novelty, and processing of rewards.
- Norepinephrine (blue) related to arousal modulation, signal-to noise ratios in cortical regions, cognitive preparation for urgent stimuli.
Thalamus and ADHD
Thalamus plays a key role in both the reward and alerting network.
* While the thalamus is a relay center for most of the sensory information, it also plays a role in alertness. Dysregulated thalamic circuitry could be related to the under arousal that is associated with
ADHD
* Connections between the thalamus and basal ganglia, particularly
between medial and anterior dorsal thalamus and the putamen, were
related to spatial working memory and also altered in ADHD
True or False: The Reward Network functions typically in the brain for those who have ADHD
- False
Functioning is abnormal when
ADHD is present
True or False: The Alerting Network is weaker in those who have ADHD
True
What is the Default Mode Network?
- DMN are regions with elevated metabolic activities when the brain was not engaged in a task, conversation, or other activity that required focus.
In those with ADHD, the DMN doesn’t turn off when focus is required, resulting in competition for cognitive resources.
What are the factors in Mirsky’s Model of Attention?
In 1991, Mirsky and colleagues proposed a three-factor model of
attention: focus, sustain, and shift.
They expanded the model in 1996 to include encode, focus/execute, and stabilize.
Define encoding as related to attention
the ability to register information, as well as holding information briefly in mind while performing some action on it.
* Overlaps with the construct of Working Memory
Define sustain as related to attention
Maintaining attention on some specific stimulus for an extended interval of time.
Define stability as related to attention
A reflection of the variability of response reaction time. * Subsequent studies suggest that stability is associated with sustain