Neurophysiology BRS Flashcards
Origin of Preganglionic Nerve
Sympathetic
Parasympathetic
Sympathetic: Nuclei of Spinal Segment (Thoracolumbar: T12-L3)
Parasympathetic: Nuclei of Cranial Nerves, Spinal Cord Segment (Craniosacral: S2-S4)
Length of Preganglionic Nerve Axon
Para vs Sympa
Para: Long
Sym: Short
Neurotransmitter in ganglion
Para vs Sympa
Ach both
Receptor in ganglion
Para vs Sym
Para Nicotinic
Sym Nicotinic
Length of postganglionic nerve axon
Para vs Sym
Para short
Sym long
Effector organs
Para vs Sym vs Somatic
Para and Sym: Smooth and cardiac muscle, glands
Somatic: Skeletal
Neurotransmitter in Effector organs
Para vs Sym vs Soma
Para: Ach
Sym: Norepinephrine (exc gland: Ach)
Skeletal: Ach
Receptor types in effector organs
Para vs Sym vs Som
Para: Muscarinic
Sym: A1, A2, B1, B2
Soma: Nicotinic
Specialized ganglion of the SNS
Adrenal Medulla
Chromaffin cells secrete
80% Norepinephrine
20% Epinephrine
A tumor of the renal medulla that secretes excessive amounts of Catecholamines
Pheochromocytoma
Neurotransmitters of the ANS
Adrenergic neurons: Norepinephrine
Cholinergic Neurons: Acetylcholine
Noncholinergic, nonadrenergic: Substance P, VIP, NO
Receptor Types in the ANS
Adrenergic receptors
A1, A2, B1, B2
Cholinergic receptors
Nicotinic, Muscarinic
G Proteins of the adrenergic receptors
Adrenergic:
A1: Gq
A2: Gi
B1: Gs
B2: Gq
G Proteins of the Cholinergic Receptors
Nicotinic: -
Muscarinic:
M2: Gi
M3: Gq